Laboratory studies involving crystal growth inhibition and plaque biofilm calcification were conducted to confirm the anticalculus potential of a dual-action whitening dentifrice containing sodium hexametaphosphate, a novel, enamel-safe, antitartar agent. Calcium hydroxyapatite crystal growth was significantly inhibited following direct supernate treatments by hexametaphosphate in solution and when formulated into the dual-action whitening dentifrice. Similarly, plaque biofilm calcification was significantly inhibited by supernate treatments of the hexametaphosphate whitening dentifrice.
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