Publications by authors named "Elaine M Husni"

Objective: Patients with immune-mediated inflammatory diseases (IMIDs) receiving B cell-depleting therapy (BCDT) are among the most vulnerable to severe COVID-19, as well as the most likely to suboptimally respond to SARS-CoV-2 vaccines. However, little is known about the frequency or severity of breakthrough infection in this population. We retrospectively analyzed a large group of vaccinated IMID patients undergoing BCDT in order to identify breakthrough COVID-19 infections and assess their outcomes.

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Article Synopsis
  • - A systematic review was conducted to evaluate the connection between type 2 diabetes and osteoarthritis (OA), with the aim of assessing whether previous observational studies had consistent findings.
  • - The review analyzed ten studies totaling 16,742 patients, finding a significant association between type 2 diabetes and the presence or development of OA, reflected by an odds ratio (OR) of 1.21.
  • - The analysis indicated that even after accounting for weight and BMI, type 2 diabetes was linked to a greater likelihood of OA, with an OR of 1.25 in studies that adjusted for these factors.
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