Synopsis of recent research by authors named "Elaine K Moen"
- Elaine K Moen's recent research primarily focuses on the safety and efficacy of gene therapy using hepatocyte growth factor (HGF) plasmid injections aimed at improving limb perfusion and wound healing in patients suffering from ischemic lower extremity ulceration.
- The findings from the HGF-0205 trial, a randomized placebo-controlled multi-center study, indicate that HGF angiogenic gene therapy significantly improves tissue oxygenation (TcPO2) in patients with critical limb ischemia who lack revascularization options.
- The study employed a novel modified HGF gene delivery technique involving multiple intramuscular injections under ultrasound guidance, highlighting an innovative approach to treating severe lower extremity ischemia.
