Bing-Neel syndrome: a case report and systematic review of clinical manifestations, diagnosis, and treatment options.

Background: Bing-Neel syndrome is an extremely rare neurologic complication of Waldenström macroglobulinemia (WM) that was first described in 1936. It is associated with central nervous system infiltration by neoplastic lymphoplasmacytoid and plasma cells with or without cerebrospinal fluid (CSF) hyperglobulinemia.

Case Report: We report a case of a 69-year-old white man with a 10-year history of WM.