Larvicidal activity of terpenes and their derivatives against Aedes aegypti: a systematic review and meta-analysis.

Aedes aegypti (Diptera: Culicidae) is the primary arthropod vector responsible for the transmission of dengue, which is present in more than one hundred countries. The application of synthetic larvicides is one of the most common strategies used for dengue control, but their prolonged use can cause larvicide resistance or tolerance, environmental damage, and have toxic effects on human and animal health. Thus, faced with this problem, there have been increasing efforts to find alternative larvicides against Ae.