Publications by authors named "Elaheh Rezaei"
The synthesis of all-carbon quaternary stereocenters containing nitriles is a very important and challenging subject in organic chemistry. We used a biocatalytic approach under mild conditions to obtain new derivatives of these scaffolds by oxidation of catechols by laccase (Novozym 51003) to afford -quinones and 1,4-addition of a series of carbon nucleophiles containing tertiary alkyle nitriles to these intermediates. Using this approach, α-cyano carbonyls bearing a quaternary stereocenter were also prepared.
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- Mesenchymal stromal cells (MSCs) are multipotent stem cells derived from fat and bone marrow, increasingly recognized for their roles in tissue engineering and regenerative medicine, particularly in generating skin cells and reducing inflammation.* -
- MSCs have demonstrated antimicrobial properties that can combat bacterial infections when used therapeutically, although retaining these cells post-transplant remains a challenge, especially in low-oxygen environments.* -
- Understanding how hypoxia affects MSC function is essential, as it influences their differentiation and inflammatory responses, presenting new opportunities for MSC-based treatments in oxygen-deprived wound infections.*
Background And Objectives: Leptospirosis, an infection caused by pathogenic leptospires, is associated with insufficient sanitation and poverty. Leptospira is transmitted through contact with contaminated urine of reservoir animals. The primary objective of this study was to clone and sequence the gene present in local and vaccine serovars.
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