Publications by authors named "Eladio Fernandez-Liz"
Background: In response to the rising population of nursing home residents with frailty and multimorbidity, optimizing medication safety through drug utilization review and addressing medication-related problems (MRPs) is imperative. Clinical decision support systems help reduce medication errors and detect potential MRPs, as well as medication reviews performed by a multidisciplinary team, but these combined assessments are not commonly performed. The objective of this study was to evaluate the impact on medication plans of a multidisciplinary team intervention in nursing homes, by analyzing the medication plan before and after the intervention and assessing whether the recommendations given had been implemented.
View Article and Find Full Text PDFAging correlates with increased frailty, multi-morbidity, and chronic diseases. Furthermore, treating the aged often entails polypharmacy to achieve optimal disease management, augmenting medication-related problems (MRPs). Few guidelines and tools address the problem of polypharmacy and MRPs, mainly within the institutionalized elderly population.
View Article and Find Full Text PDFPrevalence of Gabapentinoids and Central Nervous System Depressant Drugs, and Their Association with Risk Factors for Respiratory Depression in Primary Care Patients.
Clin Drug Investig
May 2022
Article Synopsis
- A study was conducted to analyze the use of gabapentinoids (medications often used for nerve pain and seizures) among patients in Barcelona, focusing particularly on their use with other central nervous system depressants like opioids and anxiolytics due to the risk of severe respiratory depression.
- * The research involved over 363,000 residents and found that 3.0% were prescribed gabapentinoids, with usage significantly higher among older age groups, particularly those aged 65 and above.
- * Nearly half of the patients were on multiple medications (polypharmacy), and 25.9% had renal function issues that required dosage adjustments for the medications.
Long-term effectiveness of an intervention to enhance mirabegron use revision and its deprescribing: 36-month follow-up of a quasi-experimental trial in primary care.
Curr Med Res Opin
April 2021
Objective: This is a follow-up study from a multicenter, prospective, before-and-after quasi-experimental, controlled trial to assess effectiveness at 36 months of an intervention designed to promote the revision and deprescribing of mirabegron in primary care in patients with overactive bladder.
Methods: Intervention included patients who attended in 17 PHCs located in North Barcelona; control included patients who attended in the other 34 PHCs located in South, East and West Barcelona. The primary endpoint was mirabegron review and deprescribing when GPs considered appropriate, which was measured by the percentage of change of the number of patients with treatment at 36 months compared to the baseline.
Background: Overactive bladder is a composite of lower urinary tract storage symptoms. Pharmacological treatment is widely employed despite markedly modest efficacy data, adverse effects, and costs for the health system.
Aim: To determine the 12-month efficacy of an intervention delivered by GPs on mirabegron revision and, if appropriate, discontinuation of treatment.
Unlabelled: What is already known about this subject. Knowledge of prescription patterns in primary health care is an important tool in rational drug therapy. Age and gender are the principal determining factors of cost variability between medical practices, due to drug prescriptions.
View Article and Find Full Text PDFObjectives: To evaluate existing information on questions of therapy coordination between primary and hospital care and to identify activities with positive results that could be adapted at the local level.
Design: Systematic review.
Data Sources: MEDLINE, SIETES, and Cochrane systematic review databases were searched for articles published between January 1990 and August 2005.