Publications by authors named "Eladio Busto"
Arch Bronconeumol
August 2023
Article Synopsis
- Blood eosinophil count (BEC) is used for evaluating T2 inflammation in severe asthma, but its connection to tissue changes remains unclear; bronchial biopsy may clarify this issue with a standardized pathological scoring system.
- A systematic evaluation of various tissue characteristics (like eosinophilic count and goblet cell hyperplasia) was conducted on biopsies from severe uncontrolled asthma patients, showing strong agreement among pathologists and significant correlations between BEC, tissue eosinophil count (TEC), and fractional exhaled nitric oxide (FeNO).
- The study concludes that a standardized assessment of bronchial biopsy can enhance the understanding and classification of severe uncontrolled asthma, especially in patients undergoing treatment with oral corticosteroids.
