Immune cells release cytokines, which are crucial for activating the immune response in target cells, but the exact mechanisms behind this process are still being studied.
This review discusses cytokine secretion through exocytosis, focusing on how cytokines are trafficked and the roles of sorting receptors and cytoskeletal rearrangements in their release.
It also explores non-classical cytokine release mechanisms, such as inflammasome or autophagy pathways, emphasizing the importance of understanding these processes for potential therapeutic applications in immune-related diseases.