Anti-diabetic activities of phenolic compounds of sp., an endophyte isolated from the leaves of desert plants growing in Egypt.

Six phenolic compounds (talaroflavone (1), alternarienoic acid (2), altenuene (3), altenusin (4), alternariol (5), and alternariol-5--methyl ether (6)) were isolated from the solid rice culture media of sp., an endophyte isolated from the fresh leaves of three desert plants, Dammer (Solanaceae), L. (Amaryllidaceae) and L.

: new secondary metabolites and their cytotoxic activities.

Two new compounds, 11-methoxy-11,12-dihydro phytuberin (2) and 9-methoxy-benzocyclononan-7-one (6), together with twenty-six known ones were isolated from (Solanaceae). Their planar structure was established by extensive spectroscopic analyses. The absolute configuration of compound 6 was determined by time dependent density functional theory calculations (TDDFT).

A new homoisoflavan from Balf. f. resin: α-glucosidase and COX-II inhibitory activity.

A new homoisoflavan, identified as (3 )-7-hydroxy-3',4'-methylenedioxyhomoisoflavan, was isolated from Balf. f. resin.

A unique C-linked chalcone-dihydrochalcone dimer from resin.

A new C-linked chalcone-dihydrochalcone dimer, named dracidione, was isolated from the ethyl acetate extract of dragon's blood resin of Balf. f. Structure elucidation of the new compound was carried out by means of one- and two-dimensional NMR spectroscopy in addition to high resolution mass spectrometry.

A new glucoside with a potent α-glucosidase inhibitory activity from .

A new glucoside, 3-methoxy-4---D-glucopyranosyl-methyl benzoate, has been isolated from along with five known compounds through bioactivity guided fractionation of the total plant methanolic extract towards -glucosidase inhibitory activity. All the isolated compounds were tested for their inhibitory effect on -glucosidase enzyme. As a result, four of them showed a potent inhibitory activity and thus constitute a therapeutic approach to decrease postprandial hyperglycemia in diabetic patients.

Essential oil of Daucus glaber Forssk.

The composition of the essential oil of the fruits, leaves and stems of Daucus glaber Forssk has been studied by GC/MS. It was found that, the essential oil of the fruits consists of monoterpene hydrocarbons (limonene and sylvestrene are the majors) and phenylpropanoids (elemicin is the major). Sylvestrene has never been reported before in the essential oil of any Daucus species.