Comparison between classic 'Fisch' and 'corner-tag' meatoplasty techniques after canal wall down tympanomastoidectomy.

Purpose: To compare outcomes of two different methods of meatoplasty following Canal Wall-Down tympanomastoidectomy.

Methods: A retrospective case review study of 48 patients with non-complicated unsafe chronic suppurative otitis media candidate for post-auricular canal wall-down tympanomastoidectomy via a post-auricular approach at Otolaryngology department, Benha university hospitals from January 2021 to January 2023, all were operated for the first time, and divided into 2 groups each of 24 patients. Group A submitted for classic 'Fisch', and group B 'Corner-Tag' meatoplasty.

Nanoscale poly(acrylic acid)-based hydrogels prepared via a green single-step approach for application as low-viscosity biomimetic fluid tears.

The present work reports a nanotechnology strategy to prepare a low-viscosity poly(acrylic acid) (PAAc)-based tear substitute with enhanced efficacy and compliance. Specifically, nanogels composed of PAAc and polyvinylpyrrolidone (PVP) were prepared by adapting an ionizing radiation method. For this purpose, different aqueous systems: PVP/PAAc nanoparticulate complexes, PVP/acrylic acid (AAc), N-vinylpyrrolidone (N-VP)/PAAc, and N-VP/AAc were exposed to gamma rays.

Radiation induced crosslinking of polyacrylamide incorporated low molecular weights natural polymers for possible use in the agricultural applications.

Superabsorbent hydrogels based on polyacrylamide (PAAm) and Na-alginate (Alg) or chitosan (CS) were synthesized by γ-rays. The effect of dose and copolymer composition on gel content and water absorbency of PAAm/Alg, PAAm/CS and PAAm/Alg/CS hydrogels were studied. The gel content and water absorbency follows the order PAAm/Alg>PAAm/Alg/CS>PAAm/CS.

Description of D-glucosamine immobilization kinetics onto poly(lactic acid) surface via a multistep physicochemical approach for preparation of novel active biomaterials.

Poly(lactic acid) (PLA) has shown much success in the preparation of tissue engineering scaffolds as it can be fabricated with a tailored architecture. However, the PLA surface has drawbacks including the lack of biofunctional motifs which are essential for high affinity to biological cells. Therefore, this study describes a multistep physicochemical approach for the immobilization of d-glucosamine (GlcN), a naturally occurring monosaccharide having many biological functions, on the PLA surface aiming at enhancing the cell proliferation activity.

Gamma irradiated chitosan and its derivatives as antioxidants for minced chicken.

Ionizing radiation and oxidizing agent like H2O2 were used to degrade chitosan (CS) and its derivatives; N-maleoylchitosan (NMCS), and N-phthaloylchitosan (NPhCS). The structure changes were detected using gel permeation chromatography (GPC). The results revealed that ionizing radiation degraded CS, MNCS, NPhCS and altered their molecular weights and antioxidant activity.

Developing the potential ophthalmic applications of pilocarpine entrapped into polyvinylpyrrolidone-poly(acrylic acid) nanogel dispersions prepared by γ radiation.

The aim of this study was to improve the stability and bioavailability of pilocarpine in order to maintain an adequate concentration of the pilocarpine at the site of action for prolonged period of time. Thus, pH-sensitive polyvinylpyrrolidone-poly(acrylic acid) (PVP/PAAc) nanogels prepared by γ radiation-induced polymerization of acrylic acid (AAc) in an aqueous solution of polyvinylpyrrolidone (PVP) as a template polymer were used to encapsulate pilocarpine. Factors affecting size and encapsulation efficiency were optimized to obtain nanogel suitable for entrapping drug efficiently.

Improvement of antioxidant activity of chitosan by chemical treatment and ionizing radiation.

Modification of chitosan (CS) to N-maleoylchitosan (NMCS), N-phthaloylchitosan (NPhCS) and sulfonated-chitosan (SCS) was done using maleic anhydride, phthalic anhydride and chlorosulfonic acid, respectively followed by exposing them to γ-rays at different doses. The molecular weights and structural changes of irradiated chitosan derivatives were determined by GPC, FT-IR and UV-vis spectrophotometer. The molecular weights decreased with increasing irradiation dose.

Adsorption and desorption of phosphate and nitrate ions using quaternary (polypropylene-g-N,N-dimethylamino ethylmethacrylate) graft copolymer.

Study has been made on the preparation of functionalized copolymer by grafting N,N-(dimethylaminoethyl) methacrylate (DMAEMA) onto polypropylene (PP) films using gamma-irradiation technique. The effect of monomer concentration and irradiation dose on the grafting yield was studied. It was found that grafting yield increases with increasing the monomer concentration and irradiation dose.

Radiation synthesis of poly(ethylene glycol)/acrylic acid hydrogel as carrier for site specific drug delivery.

pH-sensitive hydrogels were prepared from poly(ethylene glycol) (PEG) and acrylic acid (AAc) in aqueous solution employing gamma-radiation-induced copolymerization and crosslinking. The swelling behavior of the prepared hydrogels was determined by investigating the time and pH-dependent swelling of the (PEG/AAc) hydrogels of different PEG content. The effect of environmental parameters such as pH and ionic strength on the swelling kinetics was studied.