Intravascular Cleave the Host Immune and Hemostatic Signaling Molecule Sphingosine-1-Phosphate Tegumental Alkaline Phosphatase.

Schistosomes are parasitic flatworms that infect the vasculature of >200 million people around the world. These long-lived parasites do not appear to provoke blood clot formation or obvious inflammation around them . Proteins expressed at the host-parasite interface (such as alkaline phosphatase, SmAP) are likely key to these abilities.