Toxoplasmosis and pregnancy: an analytical study in Zagazig, Egypt.

The sera of 72 women with a history of abortion (sporadic or habitual abortion) or perinatal complications were examined for Toxoplasma antibodies using indirect immunofluorescent antibody test (IFAT). It was found that 27.8% of them were positive for toxoplasmosis with geometric mean titre of 1/64.

Serological studies on toxoplasmosis in Zagazig slaughterhouse.

This study intended to estimate the prevalence of Toxoplasma antibodies among farm animals in Zagazig slaughterhouses using indirect haemagglutination test (I.H.A.

Effect of Hymenolepis nana on the mouse ileal mucosal cells: histochemical studies.

Histochemical studies of the ileal mucosal cells of mice experimentally infected with H. nana revealed definite increase in mucous secretions indicating increased activity of the goblet cells in response to mucosal irritation. The activity of acid phosphatase was also increased representing a sort of defence mechanism against the attached worms.

Effect of some drugs on some histopathological and immunological aspects of experimental trichinosis in albino rats.

The present work is concerned with study of the effects of praziquantel, thiabendazole, mebendazole, cyclophosphamide and cortisone on histopathology of the small intestine (during intestinal phase) and skeletal muscles (during muscular phase), in addition to T. lymphocytes count and serum IgG estimation in experimental trichinosis in albino rats. Praziquantel has no effect on the histopathology of small intestine or skeletal muscles.

Echinococcosis in camels as revealed by indirect haemagglutination test in Belbas.

This study aimed to estimate the prevalence of Echinococcus antibodies in camels using the indirect haemagglutination test (I.H.A.

Cell-mediated immune response in experimental infection with H. heterophyes.

Experimental infection of puppies with Heterophyes heterophyes was associated with marked cell-mediated immune response that manifested itself by increase of T-cell count and leucocyte migration. The degree of cell-mediated immune response was inversely proportional to the intensity of infection. The significance of the results was discussed.

The role of single sample detection of specific anti-Toxoplasma IgM in accurate evaluation of seroconversion during acquired toxoplasmosis.

Specific IgM anti-Toxoplasma antibodies were sought in 94 serum samples by means of D.S. IgM ELISA.

The effect of some drugs on acute toxoplasmosis in mice.

The effect of some chemotherapeutics, on the course of acute toxoplasmosis in experimentally infected mice was studied. Obtained results showed that, praziquantel, levamisole had no effect on acute toxoplasmosis, while trimethoprim-sulphamethoxazole and clindamycin showed some prophylactic effect on acute toxoplasmosis in mice.

Effect of diet on experimental giardiasis.

Protein and fat deficiency diet produced significant reduction of Giardia cysts in rats, while vitamin A, D and iron deficiency diet had no effect on cyst count. On the other hand pathological changes due to Giardia infection encountered in small intestine and liver were aggravated by the diet deficiency induced.

Effect of ambient temperature changes on chronic toxoplasmosis in rats.

The effect of excess heat and cold on chronic toxoplasmosis was studied on rats. That was evident from the average increase in body weight, the effect on blood picture, deleterious effect of the pathology recorded in various organs, increased Toxoplasma brain cyst count, long persistence of parasites in the viscera, high antibody titre by I.H.

Effect of some anthelmintics on Hymenolepis nana in albino mice.

Mebendazole and emetine (orally and parenterally) were used to treat mice infected with H. nana. Yomesan, in a single oral dose, was also used as a standardized well-known cesticidal drug.

Comparative study between latex agglutination and indirect immunofluorescent antibody tests in diagnosis of toxoplasmosis.

The latex agglutination test (Toxolatex) was compared with the indirect immunofluorescent antibody test (IFAT) in investigating one hundred and fifty human sera. Both techniques showed 90.7% agreement.

Cross-reactions in immunodiagnosis of patients infected with Schistosoma, Fasciola and Heterophyes using ELISA.

Cross-reactions in immunodiagnosis using schistosomal soluble egg antigen (SEA) and Fasciola adult worm antigen in cases with fascioliasis, heterophyiasis and schistosomiasis were studied by ELISA techniques. False positive reactions occurred in 10% of cases with fascioliasis and heterophyiasis respectively when using schistosomal SEA. Using Fasciola crude antigen, false positive reaction occurred in 25% of cases with schistosomiasis and 35% with heterophyiasis.

Biological and haematological changes in experimental cryptosporidiosis.

In experimentally infected laboratory-bred white rats, Cryptosporidium infection rate was higher among immunosuppressed (75%) than immunocompetent ones (37.5%) with statistically insignificant difference. Cryptosporidiosis was found to be a fatal disease especially in immunosuppressed rats (50%).

Toxoplasmosis among cases of chronic tonsillitis.

One hundred cases aged 4-20 years and suffering from chronic tonsillitis were examined for Toxoplasma antibodies using indirect immunofluorescent test (IFAT). It was found that 37% of them were positive for toxoplasmosis. 41.