Splenic abscess and sickle cell disease.

This is a report of our experience with 10 cases of splenic abscess in patients with sickle cell disease (SCD). All presented with fever and abdominal pain and were found to have a tender enlarged spleen. Two were found to have a ruptured spleen and five of them were septicemic on presentation.

The patterns of oropharyngeal microflora in patients with homozygous sickle cell disease.

A controlled prospective study was carried out between 16 July 1991 and 31 January 1992 to evaluate the oropharyngeal flora in homozygous sickle cell disease (SS). Throat swabs for cultures were taken from 163 asymptomatic SS patients attending sickle cell clinics (90 children and 73 adults). Throat swabs were also taken from 84 asymptomatic healthy individuals as a control group (44 children and 40 adults).

Bacteriuria, incidence, causative microorganism, and susceptibility pattern at Qatif Central Hospital.

From August 1988 to January 1990, a total of 13,193 urine specimens were collected from inpatients and outpatients of Qatif Central Hospital, located in the Eastern Province of Saudi Arabia, to determine the incidence of significant bacteriuria, causative microorganisms, and antimicrobial susceptibility. Among these, 1004 specimens (7.6%) showed significant bacteriuria.

Incidence of major infection in sickle cell pediatric patients at Qatif Central Hospital.

During the two-year period, 20 Jumada I 1408 (January 9, 1989) to 20 Jumada I 1410 (December 18, 1989), a total of 450 pediatric patients with sickle-cell anemia were admitted to the pediatric ward of Qatif Central Hospital. Thirty-nine patients had a major infection (septicemia, meningitis, or osteomyelitis), with an incidence of 8.6%.