Nano-chitosan as a bio-enhancer for improving insecticide formulations: A study on indoxacarb and methomyl against cotton leafworm.

This study was designed to improve the effectiveness and safety of two commercial insecticides, Camvaal EC 15 % (indoxacarb) and Nudrin SP 90 % (methomyl), against Spodoptera littoralis (Boisd.) through nanotechnology. Insecticide nanoemulsions were enhanced using nano-chitosan as a natural biopolymer.

NMR-based metabolomic analysis of wild, greenhouse, and in vitro regenerated shoots of subsp. with GC-MS assessment of proximadiol.

subsp is a wild plant distributed in subtropical and east Africa extending from the north to the southern parts of Egypt. Widely used in folk medicine, it is the source of the diuretic sesquiterpene proximadiol. Nuclear magnetic resonance metabolomic analysis of polar extracts of shoots from wild, greenhouse, somatic embryos, and direct and indirect organogenic in vitro cultures was carried out.

Multi-method assessment of patients with febrile illness reveals over-diagnosis of malaria in rural Uganda.

Background: Health clinics in rural Africa are typically resource-limited. As a result, many patients presenting with fever are treated with anti-malarial drugs based only on clinical presentation. This is a considerable issue in Uganda, where malaria is routinely over-diagnosed and over-treated, constituting a wastage of resources and an elevated risk of mortality in wrongly diagnosed patients.

Novel gold nanoparticles coated with somatostatin as a potential delivery system for targeting somatostatin receptors.

Targeting of G-protein coupled receptors (GPCRs) like somatostatin-14 (SST-14) could have a potential interest in delivery of anti-cancer agents to tumor cells. Attachment of SST to different nano-carriers e.g.

Fine structure of the dorsal lingual epithelium in Tarentola annularis and Crocodylus niloticus.

The present study examined the morphological features, histological and histochemical aspect of the tongue of two reptilian species, Tarentola annularis (family: Gekkonidae) and Crocodylus niloticus (family: Crocodylidea), with different habitats, feeding patterns and behaviours, by light and scanning electron microscope. It was observed, that the bifurcation of the tongue was more visible in Tarentola annularis. Conical and filamentous papillae were observed on the lingual body of Tarentola annularis, while in Crocodylus niloticus both mechanical filiform and gustatory papillae appeared.

Effects of experimentally induced maternal hypothyroidism and hyperthyroidism on the development of rat offspring: II-the developmental pattern of neurons in relation to oxidative stress and antioxidant defense system.

Excessive concentrations of free radicals in the developing brain may lead to neurons maldevelopment and neurons damage and death. Thyroid hormones (THs) states play an important role in affecting the modulation of oxidative stress and antioxidant defense system. Thus, the objective of this study was to clarify the effect of hypothyroidism and hyperthyroidism in rat dams on the neurons development of different brain regions of their offspring at several postnatal weeks in relation to changes in the oxidative stress and antioxidant defense system.

Peptide inhibitors of the Keap1-Nrf2 protein-protein interaction.

Disruption of the interaction between the ubiquitination facilitator protein Keap1 and the cap'n'collar basic-region leucine-zipper transcription factor Nrf2 is a potential strategy to enhance expression of antioxidant and free radical detoxification gene products regulated by Nrf2. Agents that disrupt this protein-protein interaction may be useful pharmacological probes and future cancer-chemopreventive agents. We describe the structure-activity relationships for a series of peptides based upon regions of the Nrf2 Neh2 domain, of varying length and sequence, that interact with the Keap1 Kelch domain and disrupt the interaction with Nrf2.

Comparative study of the effects of experimentally induced hypothyroidism and hyperthyroidism in some brain regions in albino rats.

Thyroid hormones (THs) play a crucial role in the development and physiological functioning of different body organs especially the brain. Therefore, the objective of this study was to show the histopathological effects of the different thyroid states on some brain regions (cerebrum and cerebellum) and the skeletal features of their newborns during the postnatal development from the 1st to 3rd week. The female white albino rats were allocated into 3 groups as follows: the experimental hypothyroidism group is induced by 0.

Thyroid hormones states and brain development interactions.

The action of thyroid hormones (THs) in the brain is strictly regulated, since these hormones play a crucial role in the development and physiological functioning of the central nervous system (CNS). Disorders of the thyroid gland are among the most common endocrine maladies. Therefore, the objective of this study was to identify in broad terms the interactions between thyroid hormone states or actions and brain development.

Critical incident reports in adults: an analytical study in a teaching hospital.

Unlabelled: Self-auditing is important to improve the standard of care. In a previous study (1991--1997), we reported human error and equipment factor as the two major causes leading to critical incidents. This study analyzes the computerized database and the medical records of 71 critical incidents reported in the Department morbidity and mortality meeting between 1998--2002, in an attempt to identify factors that have led to critical incidents and compare them with our previous report.

Intra-operative heparin release during lung surgery.

Objectives: Heparin has long been thought to be biosynthesized and stored in the granules of mast cells that are most prevalent in the lungs and gastro-intestinal tract. In response to stimuli such inflammation and trauma, mast cells degranulate and consequently release heparin. This prospective study was designed to investigate if operative trauma during lung mobilization could enhance heparin release into both the pulmonary and systemic circulations.

The effects of pneumoperitoneum on respiratory mechanics during general anesthesia for bariatric surgery.

Background: The effects of pneumoperitoneum (PPM) on respiratory mechanics during bariatric surgery were investigated.

Patients And Methods: 10 patients with BMI 50.5+/-8 kg/m(2) (range 40.

Intestinal obstruction due to mesenteric panniculitis.

This report describes a case of mesenteric panniculitis in a 40-year-old male who presented with features of intestinal obstruction. Computed tomography scan showed a mass in the mesentery of small bowel. Resection of mass with associated small bowel and anastomosis resulted in complete recovery of the patient.

Primary hyperparathyroidism.

Objective: The aim of the study is to present the clinical pattern, surgical indication and management of primary hyperparathyroidism in a teaching hospital in the Kingdom of Saudi Arabia (KSA).

Methods: The records of patients who underwent surgical treatment for primary hyperparathyroidism at the King Khalid University Hospital, Riyadh, KSA from March 1992 to October 2002 were reviewed for epidemiological data, biochemical, radiological investigation, operative procedures, histopathology result, preoperative localization studies included neck ultrasonogram, neck computerized tomography and thallium-technetium subtraction scan. All patients underwent surgery under general anesthesia and procedures were bilateral, unilateral neck exploration, or minimal invasive parathyroidectomy.

Treatment of chronic fistula-in-ano using commercial fibrin glue.

Objective: To ascertain the effectiveness of commercially available fibrin glue in closing fistulae in ano.

Methods: A prospective nonrandomized trial was performed on 19 patients admitted to King Khalid University Hospital (KKUH), Riyadh, Kingdom of Saudi Arabia during the period December 2000 to November 2001. Two of the patients had multiple fistulae making a total of 21 fistulae.

Plication darn for the repair of inguinal hernia. A university hospital experience.

Objective: Recurrence rate in inguinal hernia repair is the main concern of both the surgeon and patients. The aim of this study is to evaluate the outcome in patients undergoing open inguinal hernia repair by using muscle fascial plication and nylon darn.

Methods: This technique was performed in 2 University hospitals within the Kingdom of Saudi Arabia.

Bowel anastomosis. A comparative study of various surgical techniques.

Objective: Mechanical suture (stapler) has been in use for bowel anastomosis since the second half of the 20th century, however, it became popular since it was used widely by the United States of America in the late 1960. Since it is more expensive than the conventional method, a local experimental assessment was introduced to compare stapler with conventional methods.

Methods: Eighteen local dogs were used, 36 anastomosis were assessed in the animal house operating theater of King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia between October 1998 and March 2000.

Discharging umbilicus.

Objective: Umbilical discharge is a symptom of varied pathology. Treatment policies of this clinical problem vary among different institutions. Our experience in the management of 44 patients with umbilical discharge is presented.

Atypical forms of spinal tuberculosis: case report and review of the literature.

Objective: The object of this report is to highlight some of the less known atypical features of spinal tuberculosis (TB) in the hope of facilitating early diagnosis. Pure neural arch and sacral TB is rare and the co-existence of these two as widely separated skip lesions in the same patient is even rarer.

Clinical Presentation: An unusual case of tuberculous process affecting the sacrum as well as the neural arches of upper cervical vertebrae is presented.

Laparoscopic cholecystectomy for cholelithiasis during infancy and childhood: cost analysis and review of current indications.

Eleven consecutive laparoscopic cholecystectomies (LCs) were performed between January 1994 and June 1996 compared with seven open cholecystectomies (OCs) performed previously at King Khalid University Hospital. The comparison included surgical, clinical, and economic factors, together with a review of the literature. In the laparoscopic group the main indication for cholecystectomy was symptomatic gallstones.

Laparoscopic cholecystectomy: The treatment of choice for cholelithiasis in infancy and childhood.

Twelve consecutive laparoscopic cholecystectomies (LC) were performed between January 1994 and October 1996 at King Khalid University Hospital. In all patients the indication for cholecystectomy was symptomatic gallstones. Among the 12 children, six had sickle cell disease.

Trauma cases admitted to the surgical intensive care unit--progress and outcome.

A review of the trauma admissions to the Surgical Intensive Care Unit (SICU) at King Khalid University Hospital, Riyadh during the period from 30 October 1984 to 29 October 1989 was made. A total of 181 cases constituting 15.7% of the total surgical admissions to the unit during that period were recognised.

Surgery for postintubation tracheal and tracheosubglottic stenotic lesions.

Postintubation tracheal stenosis is a recognized problem. Although its incidence has recently decreases, it is still a difficult complication to treat. We have reviewed our experience with 10 patients with tracheal stenosis over the last five years between 1990 and 1995.

Heat exhaustion during mass pilgrimage--is there a diagnostic role for pulse oximetry?

Every year over 2 million pilgrims (Hajjis) gather from different countries to perform the sacred ritual, the fifth pillar of Islam, Hajj. Several nationalities from different climates come to Saudi Arabia which is located in a subtropical area with a hot and humid climate during the long summer season. This undertaking is characterised by several days of continuous physical, spiritual, and emotional exertion following their homeland.