In vitro and in vivo effects of [Ni(M5FTSC)2Cl2] complex in cancer: preliminary tests.

The human colon adenocarcinoma-derived cell line CaCo-2 male Swiss mice and male Sprague-Dawley rats were used as model systems to study the effects of nickel (II), 5-methyl-2-furaldehyde thiosemicarbazone ligand and their complex. The stimulation effect of the complex was obtained with low concentrations from 3.7 x 10(-7) to 3.