[Retrospective analyzes of patients with meningococcal sepsis and meningitis during the period of ten years (1995-2004)].

Unlabelled: Meningococcal disease is the most significant cause of morbidity and mortality even in the most developed socio-economic surroundings. Meningococcal sepsis and meningitis are caused by Neisseria meningitidis (NM), which is surrounded by polysaharide capsule, which is the main factor of virulence.

The Goal Of The Work: was to confirm the frequency and characteristics of meningococcal disease as well as the justification of introducing vaccination.

[Hepatitis C virus infection in hemodialysis patients in General Hospital Gracanica].

Purpose: It is estimated that 10-20 % patients on hemodialysis therapy have hepatitis C virus infection with big geographic and individual variability in HCV prevalence between different hemodialysis centers.

Objectives: To determine prevalence of HCV infection among hemodialysis patients in Hemodialysis Unit of General Hospital Gracanica and to make epidemiological, clinical, biochemical and virusological analysis in anti-HCV positive patients. WORK METHODS: 58 patients that were hemodialyse during 2000 year in Hemodialysis Unit Gracanica were included in this study.

[Immune response to Engerix-B vaccine in employees at the Clinic for Infectious Diseases in Tuzla].

The adults died more frequents from the diseases that could be prevented by vaccinae. To data from WHO HBV infection numbers the nineth place on the list for causes of death. The paper from 1980 proved that chronic HBV carriers have 5-100 folds higher risk for liver carcinoma than noninfected persons lived in the same areas and had the same occupations.

[Analysis of amoxicillin-clavulanic acid (Xiclav) efficacy and the possibility of early switch from parenteral to oral therapy in the treatment of infections].

Early transition from parenteral to oral antibiotic therapy switch therapy play a major role in treatment because of adverse reactions of long parenteral therapy. In the prospective, comparative and randomized clinical study the efficacy of two treatment regimens were analyzed: XICLAV (amoxicillin + clavulanic acid): parenteral regiment with early transition to oral therapy and parenteral regimen in patients with bacterial infections without transition to the oral dosage form, on the other hand. In our study we've analyzed 240 hospitalized patients in the Clinic of infectious Diseases in Tuzla and Sarajevo too, so in the Institution for infectious diseases in Zenica.

Acute infectious diarrhea in children.

Introduction: Acute infectious diarrhea is a global health problem especially in infants and children, and is a leading cause of morbidity and mortality. The ethiology of acute infectious diarrhea and also biochemical, epidemiological and clinical characteristics of children dying with infectious diarrhea are investigated in this study.

Methods: 201 children, aged from 6 months to 14 years, with acute infectious diarrhea admitted to the Infectious Diseases Clinic in Tuzla in the period from 21st December 1999 to 21st December 2000 were included in the study.