Publications by authors named "Ekin I Sen"

Article Synopsis
  • The study compared the effectiveness of platelet-rich plasma (PRP) injections to saline placebo in reducing pain and improving quality of life for patients with hip osteoarthritis.
  • In total, 60 patients were divided into two groups, receiving injections over three weeks and monitored for six months, with various pain assessment tools used.
  • Results indicated that PRP injections provided no significant benefits over the saline placebo in terms of pain reduction or quality of life improvements, although some benefits were observed in the placebo group.
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  • * A total of 60 patients participated, undergoing treatments over 15 sessions, and were evaluated for pain and shoulder function using standardized scales at one and three months post-treatment.
  • * Results indicated significant short-term improvements in pain and function for the LLLT group compared to the control, but no lasting differences were observed among the groups after three months.
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  • Post-stroke depression (PSD) is common and can hinder recovery after a stroke, prompting a need for effective treatments.
  • A review of 61 studies involving over 5,800 participants found that pharmacological and psychological interventions, as well as their combination, may have favorable effects on PSD, though the evidence quality is very low.
  • The conclusion emphasizes the uncertainty about these treatments' effectiveness, calling for more rigorous research to better understand how to address depression in stroke survivors.
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Objective: This study aimed to assess the impact of conventional rehabilitation (CR) and the combination of bodyweight-supported treadmill training (BWSTT) with CR on walking speed, endurance, balance, mobility, and the quality of life in stroke survivors.

Method: In this prospective, randomized, controlled, and single-blind study, 30 stroke patients were included (ClinicalTrials.gov registration number: NCT04597658 date: October 22, 2020).

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Background: Many formulations and dosing regimens are available for hyaluronic acid (HA).

Objective: To compare different doses of linear, high-molecular weight (HMW) HA injections among patients with knee osteoarthritis (OA).

Methods: Hundred patients were included in this randomized, single-blinded trial and randomly divided into three HA injection groups.

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  • The study aimed to examine the effects of mesotherapy on patients with mild to moderate knee osteoarthritis (KOA) by comparing it to saline injections.
  • A total of 43 patients were involved, with 28 receiving mesotherapy and 28 receiving saline, and their pain, function, and quality of life were assessed at baseline and follow-ups.
  • Results showed significant improvements in pain and physical function for the mesotherapy group compared to the saline group, indicating that mesotherapy is a safe and effective alternative treatment for KOA.
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The study aimed to evaluate the effects of traditional dysphagia therapy (TDT) and neuromuscular electrical stimulation (NMES) combined with TDT on functionality of oral intake, dysphagia symptom severity, swallowing- and voice-related quality of life, leakage, penetration-aspiration, and residue levels in patients with post-stroke dysphagia (PSD). Thirty-four patients with PSD were included in our prospective, randomized, controlled, and single-blind study. The patients were divided into two groups: (1) TDT only (control group, n = 17) and (2) TDT with NMES (experimental group, n = 17).

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Background: Dysphagia is a geriatric syndrome. Changes in the whole body that occur with aging also affect swallowing functions and cause presbyphagia. This condition may progress to oropharyngeal and/or esophageal dysphagia in the presence of secondary causes that increase in incidence with aging.

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Article Synopsis
  • Motor imagery (MI) is being investigated as a therapeutic technique to help with stroke rehabilitation, particularly in improving gait.
  • A Cochrane Review analyzed 21 studies with 762 participants and found some evidence suggesting MI, alone or with other therapies, may enhance walking speed, although the certainty of these findings is low.
  • The review highlights the need for more high-quality research to better understand MI's effects on stroke recovery, particularly regarding motor function and overall mobility.
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Objective: The aim of this study was to investigate phantom limb pain (PLP), phantom limb sensation (PLS), and residual limb pain (RLP) after lower-extremity amputation and their effect on patients' effective prosthesis use, body image, and quality of life in prosthetic users.

Methods: Fifty-seven patients with lower-extremity amputation who used prosthesis for at least three months were included in our study. PLP, PLS, and RLP were evaluated via the prosthesis evaluation questionnaire (PEQ).

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In the prospective, randomized, controlled multicenter study, 100 patients who were clinically diagnosed with sarcopenia were assigned to either a home-based exercise group or a control group. The home-based training program included exercises with gradually increasing intensity comprising posture, stretching and upper- and lower-extremity muscle-strengthening exercises, balance and coordination exercises, and gait training. Before and 3 months after the exercise program, all the patients were evaluated.

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  • * The study addresses the lack of specialists for dysphagia in hospitals and aims to unify opinions among medical professionals on managing this condition in stroke patients.
  • * A multidisciplinary team developed 45 consensus recommendations to help with the diagnosis, management, and follow-up of dysphagia in stroke patients, primarily focusing on practices relevant to Turkey, but applicable to broader clinical settings.
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  • Dysphagia is a common complication of stroke, indicating a poorer recovery and lasting effects.
  • The guideline provides answers to clinical questions on managing, diagnosing, and rehabilitating patients with dysphagia, featuring detailed algorithms.
  • Written by a multidisciplinary team, it includes 117 recommendations divided into management (45 items) and rehabilitation (72 items) for stroke patients.
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  • This study investigated how microprocessor-controlled prosthetic knees affect mobility, body image, depression, and overall quality of life in patients with unilateral transfemoral amputations (TFAs).
  • Thirty patients participated in a 12-week clinical study, using various scales to evaluate changes in locomotion, body perception, depression levels, and quality of life before and after using the MPK.
  • Results showed significant improvements across all measured areas, indicating that MPK use enhances mobility, body image, and mental health, leading to a better quality of life for TFA patients.
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Breast cancer-related lymphedema (BCRL) is a potentially debilitating complication of breast cancer and its treatment. The aim of this study was to determine the efficacy of manual lymphatic drainage (MLD) added to multilayer compressive bandage treatment in addition to an exercise program, on arm volume, subjective symptoms, upper limb functions, and health-related quality of life (HRQoL) in patients with BCRL. This prospective, randomized, single-blind interventional trial involved 54 patients with BCRL.

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  • This study investigates the effectiveness of intra-articular injections of Prostrolane® peptide compared to hyaluronic acid (HA) and platelet-rich plasma (PRP) for treating knee osteoarthritis (OA) pain and function.
  • Fifty-four OA patients were randomly divided into three groups (HA, peptide, and PRP) and evaluated at multiple points using pain and function assessment tools.
  • While all treatment groups experienced pain relief after one week, the peptide group showed significantly better results in WOMAC pain scores after three months compared to the HA and PRP groups.
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To investigate the effects of dextrose prolotherapy in patients with knee osteoarthritis (KOA). A prospective, randomized-controlled interventional trial. An outpatient pain medicine clinic.

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Introduction: This study determined the effects of whole-body vibration (WBV) and high-impact exercises on postmenopausal women.

Materials And Methods: In this randomized controlled 6-month interventional trial, 58 eligible postmenopausal women were assigned to WBV training group, high-impact training group, or control group. Bone mineral density (BMD) of the lumbar spine and femur were measured by dual-energy X-ray absorptiometry.

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Purpose: Dysphagia is known to be a disorder of the swallowing function, and is a growing health problem in aging populations. Swallowing screening tests have mostly been studied in comorbidities such as stroke associated with old age. There is no simple, quick and easy screening test to best determine the risk of oropharyngeal dysphagia in geriatric guidelines.

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Background: The interest in biological treatments that have the potential to modify cartilage biology has gradually increased in recent years.

Objective: The aim of our study was to investigate the effects of intra-articular platelet-rich plasma (IA-PRP) injections on the femoral cartilage thickness, pain, functional status, and quality of life of patients with knee osteoarthritis.

Methods: A total of 71 patients (109 knees) with knee osteoarthritis who were administered IA-PRP injections twice with two-week intervals were included in this study.

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  • The study aimed to identify swallowing difficulties related to food consistency in participants aged 65 and older without any underlying diseases affecting swallowing functions, focusing on oropharyngeal dysphagia (OD).
  • It involved 883 participants in a multicenter cross-sectional study, using various assessments to analyze their swallowing capabilities and quality of life related to eating.
  • Results showed significant differences in swallowing difficulties based on food consistency, highlighting that mixed food content had the highest diagnostic odds for OD, while thick liquids had better specificity in diagnosing swallowing issues.
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Objective: The aim of this study was to evaluate the efficacy of ultrasound-guided suprascapular block treatment in patients with painful hemiplegic shoulder whose pain was not reduced after conservative treatment.

Design: The patients were those whose hemiplegic shoulder pain was not reduced by standard conservative treatment prior to discharge. The study group (n = 21) included patients who had undergone an ultrasound-guided suprascapular nerve block (SSNB).

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