Metabolites Obtained from Boraginaceae Plants as Potential Cosmetic Ingredients-A Review.

One of the challenges of the pharmaceutical and cosmetic industries is to deliver biochemical compounds that can be advantageous for the skin. Research on Boraginaceae taxa has confirmed their use in traditional medicine and proved the potential biological importance of various molecules in cosmetology. The main classes of valuable compounds associated with Boraginaceae taxa are fatty acids, including γ-linolenic acid, essential oils, phenolic acids (e.

Efficient Production of Some Bioactive Depsides and Simple Phenolic Acids by Microshoots of (Purple Aronia) Agitated Cultures as the Result of Feeding Strategy with Four Different Biogenetic Precursors.

A precursor feeding strategy was used for the first time in agitated microshoot cultures of . This strategy involved the addition of biogenetic precursors of simple phenolic acids (phenylalanine, cinnamic acid, and benzoic acid) and depsides (caffeic acid) into the culture media, with an assessment of its effect on the production of these bioactive compounds. The in vitro cultures were maintained in Murashige-Skoog medium (1 mg/L BAP and 1 mg/L NAA).

Biological Activities of Natural Products III.

The search for natural products that display biological activity is invariably an attractive research area for scientific centers and teams from around the world [...

Phytochemical Profiling, Antioxidant and Tyrosinase Regulatory Activities of Extracts from Herb, Leaf and In Vitro Culture of (Yarrow).

L. is one of the most known medicinal plants with a broad spectrum of applications in the treatment of inflammation, pain, microbial infections and gastrointestinal disorders. In recent years, the extracts from have also been applied in cosmetics with cleansing, moisturizing, shooting, conditioning and skin-lightening properties.

-A Rare Species with High Medicinal Potential.

(Schisandraceae) is a plant species endemic to Yunnan Province in China and is little known in Europe and America. To date, few studies, mainly performed by Chinese researchers, have been conducted on . The chemical composition of this plant is dominated by lignans (dibenzocyclooctadiene, aryltetralin, dibenzylbutane), polyphenols (phenolic acids, flavonoids), triterpenoids, and nortriterpenoids.

(Vine Grape) as a Valuable Cosmetic Raw Material.

This review refers to botanical, ecological and phytochemical characteristics of L. (vine grape)-a species, the valuable properties of which are widely exploited in the food industry and in recent times in medicine as well as in phytocosmetology. The general characteristic of , followed by the chemical composition and biological activities of different extracts obtained from the plant (fruit, skin, pomace, seed, leaf and stem extracts), are provided.

Improvement in the Biosynthesis of Antioxidant-Active Metabolites in In Vitro Cultures of (Brassicaceae) by Biotechnological Methods/Elicitation and Precursor Feeding.

This study aimed to establish the in vitro shoot culture of L. and its ability to produce antioxidant bioactive compounds. The Murashige and Skoog (MS) medium variants, containing different concentrations (0.

Comparative Analysis of Metabolic Variations, Antioxidant Profiles and Antimicrobial Activity of (Chia) Seed, Sprout, Leaf, Flower, Root and Herb Extracts.

The purpose of this study was to evaluate the phytochemical profiles of the seeds, sprouts, leaves, flowers, roots and herb of and to demonstrate their significant contribution to antioxidant and antimicrobial activities. Applied methods were: HPLC-DAD coupled with post-column derivatization with ABTS reagent, untargeted metabolomics performed by LC-Q-Orbitrap HRMS, and two-fold micro-dilution broth method, which involved suspending a solution of tested compounds dissolved in DMSO in Mueller-Hinton broth for bacteria or Mueller-Hinton broth with 2% glucose for fungi. Metabolomic profiling using LC-Q-Orbitrap HRMS used in this study yielded the identification and preliminary characterization of one hundred fifteen compounds.

Different Types of cvs. (Elixir, Helos, Topas) In Vitro Cultures: A Rich Source of Bioactive Metabolites and Biological Activities of Biomass Extracts.

Microshoot agitated and bioreactor cultures (PlantForm bioreactors) of three cultivars (Elixir, Helos, Topas) were maintained in four variants of Murashige and Skoog medium (MS) supplemented with 6-benzylaminopurine (BAP) and 1-naphthaleneacetic acid (NAA) (in the range of 0.1-3.0 mg/L).

Chitosan-Based Nanoparticles as Effective Drug Delivery Systems-A review.

Chitosan-based nanoparticles (chitosan-based nanocomposites; chitosan nanoparticles; ChNPs) are promising materials that are receiving a lot of attention in the last decades. ChNPs have great potential as nanocarriers. They are able to encapsulate drugs as well as active compounds and deliver them to a specific place in the body providing a controlled release.

In Vitro Cultures of subsp. as a Source of Bioactive Phenolic Metabolites.

Some of the more than 350 species, such as and , have been used in traditional medicine and today play an important role in official phytotherapy. Other species have been less investigated, and their therapeutic potential is unknown. This is one of the few studies on subsp.

The Influence of Exogenous Phenylalanine on the Accumulation of Secondary Metabolites in Agitated Shoot Cultures of L.

This study aimed to examine the influence of the addition of a precursor (phenylalanine) on the accumulation of secondary metabolites in agitated shoot cultures of Cultures were grown on Linsmaier and Skoog (LS) medium, with plant growth regulators (0.1 mg/L α-naphthaleneacetic acid-NAA-and 0.1 mg/L 6-benzylaminopurine-BAP).

Podophyllotoxin and its derivatives: Potential anticancer agents of natural origin in cancer chemotherapy.

The use of plant secondary metabolites has gained considerable attention among clinicians in the prevention and treatment of cancer. A secondary metabolite isolated mainly from the roots and rhizomes of Podophyllum species (Berberidaceae) is aryltetralin lignan - podophyllotoxin (PTOX). The purpose of this review is to discuss the therapeutic properties of PTOX as an important anticancer compound of natural origin.

(Moutan Peony)-A Review of the Chemical Composition, Traditional and Professional Use in Medicine, Position in Cosmetics Industries, and Biotechnological Studies.

The aim of this review is to perform a systematic review of scientific papers and an in-depth analysis of the latest research related to Andrews as a valuable plant species, important in pharmacy and cosmetology. bark root- is a medicinal raw material formerly known from traditional Chinese medicine (TCM) but less common in official European medicine. It was introduced for the first time in the European Pharmacopoeia Supplement 9.

Stimulation of Lignan Production in In Vitro Cultures by Elicitation.

The study investigated the effect of elicitation with: chitosan (CH) (200 mg/L), yeast extract (YeE) (3000 mg/L), ethephon (ETH) (25 µM/L), and methyl jasmonate (MeJA) (50 µM/L), on lignan accumulation in agitated and bioreactor (Plantform temporary immersion systems) microshoot cultures of female (F) and male (M) Rehd. et Wils. (Schisandraceae) lines.

Artemisia Species with High Biological Values as a Potential Source of Medicinal and Cosmetic Raw Materials.

species play a vital role in traditional and contemporary medicine. Among them, , , , , and are the most popular. The chemical composition and bioactivity of these species have been extensively studied.

Hydroalcoholic Leaf Extract of L. Antioxidative and Anti-Inflammatory Effects Reduces Stress-Induced Behavioral and Cellular Disorders in Mice.

Stress that can occur at different levels of a person's life can cause and exacerbate various diseases. Oxidative stress and inflammation underlie this process at the cellular level. There is an urgent need to identify new and more effective therapeutic targets for the treatment of stress-induced behavioral disorders and specific drugs that affect these targets.

Fruit and Leaves as Promising New Materials of High Biological Potential: Lignan Profiling and Effect-Directed Analysis.

The effect-directed detection (EDD) of fruit and leaves extracts was performed to assess their pharmacological properties. The EDD comprised TLC-direct bioautography against , a DPPH assay, as well as α-glucosidase, lipase, tyrosinase, and acetylcholinesterase (AChE) inhibition assays. The leaf extracts showed stronger antioxidant activity than the fruit extract as well as inhibition of tyrosinase and lipase.

Phytochemical Characterization, and Antioxidant and Antimicrobial Properties of Agitated Cultures of Three Rue Species: , , and .

The in vitro cultures of the following three species of the genus were investigated: , , and . The dynamics of biomass growth and accumulation of secondary metabolites in the 3-, 4-, 5-, 6-, and 7-week growth cycle were analysed. The antioxidant capacity of the methanol extracts obtained from the biomass of the in vitro cultures was also assessed by different in vitro assays: 1,1-diphenyl-2-picrylhydrazil (DPPH), reducing power, and Fe chelating activity assays.

Biological Activities of Natural Products II.

Natural products of different origin and their potential therapeutic activities are of unceasing widespread interest to many scientific teams from all around the world [...

The Current State of Knowledge on and (Chia Seeds).

Chia seeds () are obtained from L. This raw material is distinguished by its rich chemical composition and valuable nutritional properties. It is currently referred to as "health food".

Phenylpropanoid Glycoside and Phenolic Acid Profiles and Biological Activities of Biomass Extracts from Different Types of Microshoot Cultures and Soil-Grown Plant.

Different types of microshoot cultures (agar, stationary liquid, agitated, and bioreactors) of were optimized for biomass growth and the production of phenylpropanoid glycosides and phenolic acids. Using ultra-high performance liquid chromatography with high-resolution time-of-flight mass spectrometry, the presence of verbascoside, isoverbascoside, leucoseptoside A/isomers, and cistanoside D/isomer was confirmed in the methanolic extracts obtained from all types of in vitro cultures. The compound's content was determined by ultra-high-performance liquid chromatography.

Antioxidant Potential and Enhancement of Bioactive Metabolite Production in In Vitro Cultures of L. by Biotechnological Methods.

Studies carried out using three different in vitro assays and a biological setting () demonstrated the antioxidant activity of microshoot extract. Moreover, the extract exhibited no toxicity in a brine shrimp lethality bioassay. These results indicated that microshoots are a rich, safe source of antioxidants, which encouraged us to enhance their production in vitro.

(Star Anise) and -Anethole as Valuable Raw Materials for Medicinal and Cosmetic Applications.

Hook f. (star anise) is considered an important species in Traditional Chinese Medicine and is also used in contemporary medicine in East Asian countries. It occurs in natural habitats in southeastern parts of China and Vietnam, and is cultivated in various regions in China.