Complex study of Cancer Morbidity and Inflammatory Markers, Presented in the Blood Serum of the Rural Population of Sachkhere District of Georgia.

Aim: The purpose of the study was to compare the morbidity from cancer (expressed as incidence) to the average levels of blood serum inflammatory markers in the population of the Sachkhere region (Georgia).

Methods: healthy residents of the Sachkhere district were examined. In the blood serum samples of patients, the cytokines (IL-1α, IL-10, TGF-β, IL-12, IL-17, TNF-α, IL-6) and NOx content, as well as the total antioxidant activity of the non-enzymatic system (TAA) were determined; using light microscopy, buccal micronuclei (MnB) of epithelial cells of the oral mucosa, as indicators of chromosomal disorders, were studied.