Publications by authors named "Ekaterina Y Shishova"
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Synopsis of recent research by authors named "Ekaterina Y Shishova"
- Ekaterina Y Shishova's research primarily focuses on the molecular mechanisms of lipid metabolism and enzyme specificity, emphasized through studies on phosphatidylcholine transfer protein (PC-TP) and its role in hepatic glucose production and metabolic regulation.
- Notable findings include the protective effects of genetic ablation and chemical inhibitors targeting PC-TP against diet-induced hepatic glucose production, as well as insights into amino acid recognition by arginase, a key enzyme with therapeutic implications.
- Shishova has utilized advanced techniques such as X-ray crystallography and high-throughput screening to elucidate the structural and functional relationships of enzymes, contributing significantly to the understanding of their catalytic mechanisms and potential in drug development.
