The study explores the role of human leukocyte antigens (HLA) and their haplotypes in predicting outcomes for patients with HPV-driven head and neck squamous cell carcinoma (HNSCC), particularly focusing on oropharyngeal squamous cell carcinoma (OPSCC).
Results show altered distributions of HLA antigens in HNSCC patients, with certain HLA traits combined with lifestyle factors (like alcohol and tobacco use) significantly influencing progression-free and tumor-specific survival outcomes.
The research proposes a new risk scoring system that categorizes patients into distinct risk groups, potentially enhancing prognostic capabilities for HPV-driven HNSCC.
We review our recent activity in the field of photo-induced structural dynamics in crystalline solids studied using femtosecond X-ray diffraction techniques.