Morphological and Molecular Biological Characteristics of Experimental Rat Glioblastoma Tissue Strains Induced by Different Carcinogenic Chemicals.

Unlabelled: Glioblastoma (GBM) is a highly aggressive human neoplasm with poor prognosis due to its malignancy and therapy resistance. To evaluate the efficacy of antitumor therapy, cell models are used most widely, but they are not as relevant to human GBMs as tissue models of gliomas, closely corresponding to human GBMs in cell heterogeneity. In this work, we compared three different tissue strains of rat GBM 101.

Morphofunctional Changes in Brain and Peripheral Blood in Adult and Aged Wistar Rats with AlCl-Induced Neurodegeneration.

Background: the general lifespan has been prolonged greatly during the past century, and the incidence of age-associated diseases, including neurodegenerative ones, has increased as well. However, modelling of age-related pathologies is mostly conducted on adult rodents. We studied morphofunctional changes in the brain and peripheral blood of adult Wistar rats in comparison with old Wistar rats to determine age-related physiological changes and differences in adaptive reactions to AlCl exposure.

Diatom and cyanobacteria communities on artificial polymer substrates in the Crimean coastal waters of the Black Sea.

This research on the species diversity of fouling diatoms and cyanobacteria on different polymer materials and carried out from August to November 2020 in Karantinnaya Bay of the Black Sea. There were 75 taxa of diatoms and 24 of cyanobacteria. The maximum diatoms (31 species) were on the biodegradable bag and cyanobacteria (16) on the plastic bottle.