Publications by authors named "Ekaterina Donchenko"
(AltMV) is a typical member of the genus in its morphology and genome structure; still it exhibits a number of unique features. They allow this virus to be considered a promising object for biotechnology. Virions and virus-like particles (VLPs) of AltMV are stable in a wide range of conditions, including sera of laboratory animals.
View Article and Find Full Text PDFPlant viruses and their virus-like particles (VLPs) have a lot of advantages for biotechnological applications including complete safety for humans. Alternanthera mosaic virus (AltMV) is a potentially promising object for design of novel materials. The 3D structures of AltMV virions and its VLPs were obtained by single particle EM at ~13Å resolution.
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- A new rubella vaccine candidate was developed using modified plant virus particles known as spherical particles (SPs), which show great promise due to their unique properties.
- The SPs were derived from the tobacco mosaic virus and were found to have excellent biosafety, stability, and immunogenicity, making them suitable for vaccine development.
- The vaccine candidate successfully triggered a strong immune response, particularly with the IgG1 isotype, indicating its potential effectiveness against natural rubella infection.
An increase of infertility and chronic pelvic pains syndrome, a growing level of latent diseases of this group, as well as a stably high percentage (up to 25% for infertility and up to 60% for the chronic pelvic pains syndrome) of undetermined origin raises the requirement for novel introscopic diagnostic techniques. We demonstrate abilities of optical coherence tomography (OCT) as a complementary technique to laparoscopy in diagnostics of fallopian tubes pathologies. We have acquired OCT images of different parts of fallopian tubes in norm and with morphologically proven pathology.
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