Publications by authors named "Ekaterina Chernyavskaya"
Article Synopsis
- The study analyzed homocysteine (HCy) and vitamin levels, as well as genotypes of key gene polymorphisms related to folate metabolism in children with early-stage multiple sclerosis (MS) and compared them with healthy controls and patients with long-term MS.
- Results showed elevated HCy levels in children at MS onset without any vitamin B6, B9, or B12 deficiencies, suggesting a unique metabolic issue rather than a general vitamin deficiency.
- The findings indicate that high HCy levels can serve as a marker for functional disorders in folate metabolism associated with pediatric MS, potentially guiding new prevention and treatment strategies.
Background: Epidemiological studies suggested an association between Parkinson's disease (PD) and type 2 diabetes, but less is known about type 1 diabetes (T1D) and PD.
Objective: This study sought to explore the association between T1D and PD.
Methods: We used Mendelian randomization, linkage disequilibrium score regression, and multi-tissue transcriptome-wide analysis to examine the association between PD and T1D.