Complex Genetics in Pancreatitis: Insights Gained From a New Candidate Locus Panel.

Objectives: Chronic pancreatitis is the end stage of a pathologic inflammatory syndrome with multiple etiological factors, including genetic. We hypothesized that some pancreatitis etiology originates in pancreatic acinar or duct cells and requires both injury and compensatory mechanism failure.

Methods: One hundred pancreatitis patients were assessed using a DNA sequencing panel for pancreatitis.