Publications by authors named "Ejaz Vohra"

Article Synopsis
  • - The study investigates the effectiveness of platelet-inducing human IL-11 analogs in treating dengue fever (DF) patients with low platelet counts (thrombocytopenia), conducted at Dr. Ziauddin Hospital in Karachi, Pakistan, from September 2023 to April 2024.
  • - A total of 300 DF patients were enrolled, with the treatment group experiencing significantly higher fever and headache rates compared to the control group and showing notable increases in platelet counts after five days of IL-11 treatment.
  • - Results suggest IL-11 analogs hold potential for managing DF-associated thrombocytopenia, highlighting the need for further research on treatment protocols and broader implications for DF therapy.
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Objective: To study the frequency of multiple vascular risk factors and electrophysiological severity of carpal tunnel syndrome (CTS) in Saudi diabetic patients.

Methods: This retrospective cross-sectional study was conducted in Neurology Department, King Fahd Hospital of University, Al-Khobar, Kingdom of Saudi Arabia from April 2017 to March 2018 and included 200 patients with CTS. Body parameters, such as blood pressure (BP), weight, height, and body mass index (BMI), along with laboratory and median nerve electrophysiological parameters, of diabetic and non-diabetic patients were compared, and a p-value<0.

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Toxoplasmosis is an obligate intracellular, food borne parasite disease with variable clinical presentation. Although the neurological presentation of toxoplasmosis in immunocompetent patients is uncommon, broad differential diagnosis should be kept in consideration when attending to similar patients. Twenty years old man with no known co-morbid conditions presented with fever and unilateral limb weakness for three weeks.

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Objective: To determine the safety and effectiveness of biphasic insulin aspart 30 (BIAsp 30) in type 2 diabetes subjects switched from biphasic human insulin 30 (BHI 30) in the Pakistani subgroup of the multinational, prospective, non-interventional A1chieve study.

Methods: Subjects who switched therapy from BHI 30 to BIAsp 30 were included in this analysis. Serious adverse drug reactions (SADRs, including major hypoglycaemia) and effectiveness parameters (glycated haemoglobin [HbA1c], fasting plasma glucose [FPG], postprandial plasma glucose [PPPG], systolic blood pressure [SBP]) and body weight were evaluated at the end of 24 weeks.

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Objective: To identify the frequency of risk factors in various subtypes of acute ischemic stroke according to TOAST criteria.

Study Design: Cross-sectional, observational study.

Place And Duration Of Study: Ziauddin Hospital, Karachi, from January to December 2007.

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Objective: To compare awareness of hypertension among patients attending Primary Health Care Centre (PHC) and outpatient department (OPD) of a tertiary care hospital of Karachi.

Methods: Cross sectional survey of patients more than 18 years of age without any complication of hypertension in a squatter settlement of Karachi through non-probability convenient sampling.

Results: A total 202 patients were approached, 49 (24%) were males and 153 (76%) were females.

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Objective: To detect the presence of esophageal motor disorders in diabetic patients, and to establish whether there is any difference between patients with and without neuropathy.

Methods: Fifty-six diabetic patients admitted at Department of Medicine at Ziauddin Medical University Hospital, Karachi were selected to observe if manometeric findings were different in diabetic patients with and without diabetic neuropathy.

Results: Poor glycemic control was observed amongst patients with diabetic neuropathy as compared to those without neuropathy.

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Objective: Acute Renal Failure (ARF) is a common medical problem. Delay in diagnosis is associated with increased mortality. Variety of conditions can lead to ARF.

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Objective: To see the presence of esophageal motor disorders in diabetic patients and compare it with controls at the Department of Medicine Ziauddin Medical University Hospital, Karachi.

Methods: Diabetic patients admitted at Ziauddin Medical University Hospital, Karachi were taken as study subjects, whereas age and sex matched healthy volunteers not suffering from any disease neither taking any medication for dyspepsia were taken as controls Esophageal manometry was done to see the motility disorders in diabetic patients and controls.

Results: Resting pressure of the lower esophageal sphincter in diabetics was similar to controls.

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