[Metastasizing basalioma of the temporal area or continuous extension? Surgical approach and results].

By means of histological sections the rare diagnosis of a basalioma of the temporal area with regional metastases in the parotid gland and in the neck could be verified. Subsequently the surgical treatment and the postoperative results are described. The operation consisted of an en bloc excision of the basalioma, exstirpation of the parotid gland and radical neck dissection.

[Obliteration of the bulla of the guinea pig with a Kieler bone chip].

The obliteration of the sinus frontalis after removal of the chronically inflamed and irreversibly transformed mucous is a common surgical treatment. There is no definite answer to the question of the most suitable material for obliteration. The suitability of the Kieler Knochenspan was, therefore, tested in animal experiments.

[Flap-reconstruction in mouth and oropharynx. A clinical comparison of methods (author's transl)].

The possible methods for plastic reconstruction after resection of malignant tumors in the mouth and oropharynx are reported. A total of 165 patients, operated upon between 1973 and 1980, has been reviewed. The tumor was located 26 times in the tongue, 4 times within the base of the tongue, 27 times in the floor of the mouth, 10 times in the floor of the mouth and in the tongue and 80 times in the tonsils.

[The sublingual and submandibular glands after preganglionic parasympathetic blockade. A histological, electron optical, autoradiographic and scintigraphic study on the guinea pig].

After preganglionic parasympathetic block three histological and histochemical phases could be determined in the only cholinergically innervated mucous cells of the sublingual gland. The first phase is characterized by overproduction and oversecretion. Possibly this results from acetylcholine overproduction, caused by the block, termed as "degeneration secretion" however of preganglionic origin.

[Vascular considerations and technique-planning for pectoralis major myocutaneous island flaps (author's transl)].

The relevant distribution of the blood vessels originating from the thoracoacromial artery and the technique used to raise the pectoralis major myocutaneous island flap are described. The nutrient vessel to this flap is the thoracoacromial artery and its pectoral branches. After giving off its axillary vessels this artery with its vein crosses the upper edge of the pectoralis minor muscle and passes between the pectoralis major and minor muscles.

[Histological findings following cartilage transposition in experimental animal septoplasties (author's transl)].

The histological findings following transplantation of crushed septal cartilage into the nasal septums of seven rabbits during septoplasties are reported. Living and devitalized chondrocytes were found together with loss of cartilage substance, its replacement by granulation tissue, and new cartilage and to a lesser extent new bone formation.

[Development of the vascularisation in ossicula trans- and implants (author's transl)].

The revascularisation in 30 rabbit incudes after autogenic transplantation and allogenic implantation as well as in 5 mallei of the calf after xenogenic implantation was investigated. Prior to allogenic implantation the ossicles had been treated in five different ways: 5 ossicles had been cooled down to - 20 degrees C or to - 196 degrees C respectively, 5 others had been treated with cialit (1:5000) and 5 had been freeze dried with subsequent gamma-irradiation. In the last five collectives during the process of revascularisation the sprouting tissue of the host follows the bony canaliculi of Havers.

[Deviations of septum cartilage after unilateral separation of Mucoperichondrium in rabbits (author's transl)].

In 49 rabbits the mucoperichondrium of their nasal septa was strictly unilaterally separated according to the Cottle procedure. In addition, in some rabbits only the surface of the septal cartilage was incised and in others the cartilage was cut vertically or horizontally. Four months after the operation the following alterations of the septa were seen: The separation of the mucoperichondrium from the cartilage or superficial incision of the cartilage led to a deviation to the operated left side.

[Histomorphology and resorption of longtime-implanted cartilage chips conserved in merthiolat in rhinoplasty (author's transl)].

A histological study is presented on 18 cartilage grafts, conserved in Merthiolat TM, which had been implanted for reconstruction of the caudal border of the nose for time periods of 1 month up to 11 years. These cartilage graft preparations were compared to non graft cartilage from patients died in an age of 37, 51 and 53 years respectively. Our findings show that cartilage grafts are eroded from the edge by resorption granulations of the host.

[Tympanoplasty with human dura mater preserved in cialit (author's transl)].

In 26 cases allogenetic human dura mater, conserved in CialitTM 1:5000, was used to close perforations of the eardrum instead of commonly used autogenetic fascia of the temporal muscle. In preceding animal studies, it had been found that "Cialit dura" acts as guideline and stimulates the development of new host connective tissue. In 25 human ear drums the perforations healed up without any problems.

[Artificial mesh in the reconstruction of the posterior auditory canal wall (author's transl)].

Mersilene mesh was used in the reconstruction of the posterior wall of the auditory canal in 12 radical mastoidectomy and attico-antrotomy cavities. Reestablishment of a stable metal wall occurred in 7 patients. In 2 the mesh had to be covered with soft tissue in a second procedure.

[A clinical study on allogenetic ossicle-implantation (author's transl)].

Here we report a first three years clinical experience with allogenetic ossicles in middle ear surgery. The several allogenetic implants in tympanoplasty type III are coordinated to symbolic abbreviations for documentation. The technique and biology of Cialit-preservation is summarized.

[Earstructures in one case of anencephalie (author's transl)].

According to the majority of cases under observation the following anomalies could be found: extended, separated or manifold developed crura of the stapes, reduction in the circular windings of the cochlea down to 1 1/2 with a normal development of Corti's organum, reduction of the nerve structures of the nervus cochlearis to a munimum and an open facial canal.

[The histological changes in cartilage (incus) in the middle ear after conservation--an animal study (author's transl)].

This study demonstrates the histological changes of incus cartilage after transplantation into the middle ear space of rabbits. Conservation was performed by deep-freezing, lyophilisation in connection with gamma-irradiation, or with Cialit in differing dilutions. Controlled deep-freezing at about -196 degrees C and uncontrolled deep-freezing at about -20 degrees C guarantee after transplantion the survival of some vital chondrocytes.

[Incus, controlled deepfrozen or in cialit conserved, after allogenetic implantation. An animal-experimental study with comparing histology (author's transl)].

The histological reactions to the implantation of allogenetic incus after conservation in Cialit or after controlled deepfreezing are described. After 5 months the incusses of both conservation technics show the same good tendency of revitalisation. Therefore the controlled deep-freezing technic does not offer an advantage compared to the Cialit conservation method at least for the present state of knowledge.

[Implantation of ossicles (A histological study in animals) (author's transl)].

Autogenetic and allogenetic incuses as well as xenogenetic malleus were implanted into the middle-ear of rabbits after different procedures of conservation. The process of healing was studied by histological examination. The different conservation methods are leading to different antigenic qualities of the donor material.

[The implantation of lyophilized and gamma-sterilized allogenetic incus and of lyophilized and gamma-sterilized xenogenetic malleus (calf) in rabbits and humans (author's transl)].

The histological reactions to the implantation of allogenetic and xenogenetic lyophilized and gamma-sterilized material into the middle ear of rabbits and men is described. In contrary to the behaviour of allogenetic material the xenogenetic shows a clear minor tendency of revitalisation. The reason is the antigen-antibody-reaction which takes place at the capillary network of the donor and leads to a hylinosis with following obliteration of the vascular rete.

[Observations during tonsillectomy in angiomatous phakomatoses of the head (author's transl)].

The problems encountered during tonsillectomy in a patient with a vascular malformation (flame nevus), mandibular hypertrophy, and extensive arteriovenous malformations involving the external carotid arteries are described. The inclusion of the patient in the Sturge-Weber or Klippel-Trenaunay Syndromes is discussed.

[The histological reaction of cialit preserved hyaline and elastic cartilage implanted to replace partially bony wall of the guinea-pig bulla (author's transl)].

Cialit preserved cartilage was used to fill defects of the bulla of porpoises and the histological healing was studied. Hyaline and elastic cartilage are showing an integration without reactions. The cartilage is resorbed consecutively by the recipient and substituted by bone.

[Use of the temporary osteoplastic epitympanotomy for allogenetic compound middle ear grafts (author's transl)].

The topography and the size of the single middle ear structures and the possibilities of damage are shown, as they face the otosurgeon using the temporary osteoplastic epitympanotomy in connection with middle ear implants. The landmarks and technical aids are named, which make this operation a save and quick approach for the removal of the middle ear pathologies and in the use of allogenetic material.

[Histologic-histochemical findings in the salivary glands of guinea pigs after sectioning the chorda tympani].

We investigated Gl. submandibularis and Gl. sublingualis of the guinea-pig 1, 2, 5, 7, 14 und 28 days after section of the Chorda tympani with histological-histochemical methods.

[Determination of mercury-content of tissues preserved in cialit (author's transl)].

The mercury-tissue-concentrations of implants (structures of the middle ear, bones, cartilage, dura) after preservation in solutions of cialit are mostly independent on preservation conditions, low and seem to be physiological. A positive correlation exists between the weight of the implant and the mercury-tissue concentrations. An enrichment with mercury-ions cannot be stated.