Metabolic profile of complete spinal cord injury in pons and cerebellum: A 3T 1H MRS study.

The aim of this exploratory study was the assessment of the metabolic profiles of persons with complete spinal cord injury (SCI) in three region-of-interests (pons, cerebellar vermis, and cerebellar hemisphere), with magnetic resonance spectroscopy, and their correlations to clinical scores. Group differences and association between metabolic and clinical scores were examined. Fifteen people with chronic SCI (cSCI), five people with subacute SCI (sSCI) and fourteen healthy controls were included.

Functional connectivity and amplitude of low-frequency fluctuations changes in people with complete subacute and chronic spinal cord injury.

After spinal cord injury (SCI), reorganization processes and changes in brain connectivity occur. Besides the sensorimotor cortex, the subcortical areas are strongly involved in motion and executive control. This exploratory study focusses on the cerebellum and vermis.

Emergence of mesoscale quantum phase transitions in a ferromagnet.

Mesoscale patterns as observed in, for example, ferromagnets, ferroelectrics, superconductors, monomolecular films or block copolymers reflect spatial variations of a pertinent order parameter at length scales and time scales that may be described classically. This raises the question for the relevance of mesoscale patterns near zero-temperature phase transitions, also known as quantum phase transitions. Here we report the magnetic susceptibility of LiHoF-a dipolar Ising ferromagnet-near a well-understood transverse-field quantum critical point (TF-QCP).

Clinical effectiveness of bidirectional fecal microbiota transfer in the treatment of recurrent Clostridioides difficile infections.

Background: Fecal microbiota transfer (FMT) has become a standard of care in the prevention of multiple recurrent Clostridioides difficile (rCDI) infection.

Aim: While primary cure rates range from 70-80% following a single treatment using monodirectional approaches, cure rates of combination treatment remain largely unknown.

Methods: In a retrospective case-control study, outcomes following simultaneous bidirectional FMT (bFMT) with combined endoscopic application into the upper and lower gastrointestinal tract, compared to standard routes of application (endoscopy via upper or lower gastrointestinal tract and oral capsules; abbreviated UGIT, LGIT and CAP) on day 30 and 90 after FMT were assessed.

The Torg-Pavlov ratio for the prediction of acute spinal cord injury after a minor trauma to the cervical spine.

Background Context: Acute cervical spinal cord injury (SCI) has been observed in some patients after a minor trauma to the cervical spine. The discrepancy between the severity of the trauma and the clinical symptoms has been attributed to spinal canal stenosis. However, to date, there is no universally established radiological parameter for identifying critical spinal stenosis in these patients.

[Metabolic syndrome: diagnosis and dietary intervention].

The metabolic syndrome is diagnosed according to criteria set by either WHO (obesity, high blood pressure, dyslipidemia, insulin resistance) or more recently by ATP III (National Cholesterol Education Program's Adult Treatment Panel III report). The latter emphasizes abdominal obesity, atherogenic dyslipidemia, high blood pressure and increased fasting glucose. Without presuming a nosologic entity, the metabolic syndrome is emerging as by far the most important precursor of an epidemic of cardiovascular disease, not only in Western countries.

[Malnutrition in elderly patients of an acute care clinic].

Malnutrition is associated with a higher complication rate, a higher morbidity and mortality. In-hospital patients consume up to 75% fewer calories than they would need, according to studies in international literature. For German general hospitals data are not yet available on this topic, especially for elderly people.

[Identification of wrong or inadequate nutrition of elderly patients in an acute-admissions hospital].

Background And Objective: Wrong or inadequate nutrition can lead to an increased morbidity and mortality as well as a raised perioperative rate of complications. Endangered patients should be identified quickly, reliably and cost-effectively on admission. This study aimed at developing a 3-step assessment, using a previously evaluated questionnaire.

[Myocardial involvement in carrier states for Duchenne muscular dystrophy. A rare cause of supraventricular arrhythmia].

History And Clinical Findings: Two women, both aged 54 years, were admitted because of supraventricular arrhythmias of recent onset. Patient 2 was also in heart failure. Male family members of both patients were known to have Duchenne's muscular dystrophy, of which one had died.

Three cases of malignant neoplasm, pneumonitis, and pancytopenia during treatment with low-dose methotrexate.

A 77-year-old man with chronic obstructive pulmonary disease was treated with low-dose methotrexate (7.5-15 mg per week). After 15 months a diagnosis of urothelial carcinoma of the bladder was made; after a further 6 months pneumonitis and pancytopenia developed.

Media hypertrophy in hypertensive coronary resistance vessels.

Coronary reserve is reduced in human hypertensive hypertrophy and in the model of spontaneously hypertensive rats (SHRs). In isolated coronary resistance vessels, the role of structural and functional changes was evaluated. Furthermore, the effect of long-term antihypertensive therapy was also studied.

IAEA/WHO 60Co teletherapy dosimetry service using mailed LiF dosimeters. A survey of results obtained during 1975-1982.

During 1975-1982 the International Atomic Energy Agency (IAEA) in co-operation with the World Health Organization (WHO) carried out 603 absorbed dose determinations for 60Co gamma-ray beams for 278 radiotherapy institutes in 60 countries. The participants were asked to irradiate capsules containing LiF powder to 2 Gy in 5 cm of water. The percentage of the determinations in which the deviation between the institutes quoted dose and the IAEA measured dose was within +/- 5% was 62%.

IAEA-WHO cobalt-60 teletherapy dosimetry service using mailed LiF dosemeters. A survey of results obtaining during 1970-75.

The IAEA-WHO postal dose comparison service for cobalt-60 teletherapy dosimetry is an ongoing programme aimed at improving dosimetric accuracy in IAEA-WHO Member States. LiF dosemeters were irradiated under specified conditions in a water phantom at the participating radiotherapy centres and returned to the IAEA's Dosimetry Labotatory for evaluation. The participants filled in a data sheet giving numerical values of physical factors (such as per cent depth dose, tissue-air ratio, etc.