This study aimed to develop an algorithm for modelling tooth-tooth or implant-implant support configurations for a given 4-unit fixed partial denture (FPD). : The algorithm was implemented in Rhinoceros/Grasshopper to automatically generate geometries with varying bone loss (0 mm to 3 mm), support type (tooth-tooth and implant-implant support) and bone quality (D1 to D4) for a 4-unit FPD. Afterward, a finite element analysis was carried out with a load applied to the central connector of the FPD.
View Article and Find Full Text PDFLobular carcinoma in situ (LCIS) is a precursor of invasive lobular carcinoma of the breast. LCIS cells lack cell-cell cohesion due to the loss of E-cadherin. LCIS cells grow in mammary lobules rather than in ducts.
View Article and Find Full Text PDFPurpose: Studies about success of FPDs (fixed partial dentures) mostly include restorations built by different clinicians. This results in limited comparability of the data. The aim of this study was to evaluate complications of all-ceramic FPDs built by 1 dentist between 2011 to 2023.
View Article and Find Full Text PDFJ Mater Sci Mater Med
October 2024
This study aimed to investigate adhesive shear bond strength (SBS) on an ultrafine-grained niobium alloy (UFG-Nb) that is a potential dental implant material. SBS of three adhesive systems combined with three composites to UFG-Nb was compared to corresponding SBS to Ti-6Al-4V and to zirconia. Specimens of the substrates UFG-Nb, Ti-6Al-4V and zirconia with plane surfaces were sandblasted with AlO, cleaned and dried.
View Article and Find Full Text PDFIn this study, an approach for automated parametric remodelling of the connector cross-sectional area in a CAD model of a given fixed partial denture (FPD) geometry was developed and then applied to a 4-unit FPD. The remodelling algorithm was implemented using Rhinoceros and the Grasshopper plugin. The generated CAD models were used to perform a finite element analysis with Ansys to analyse the stress distribution in an implant-supported 4-unit FPD for different connector designs.
View Article and Find Full Text PDFFront Bioeng Biotechnol
October 2023
Type I interferon-beta (IFN-β) is a crucial component of innate and adaptive immune systems inside the host. The formation of bacterial biofilms on medical implants can lead to inflammatory diseases and implant failure. Biofilms elicit IFN-β production inside the host that, in turn, restrict bacterial growth.
View Article and Find Full Text PDFComput Methods Biomech Biomed Engin
October 2024
This study aimed to develop an algorithm for modelling bone loss defects in a given mandibular geometry, with a user-defined depth, width, place, and defect type. The algorithm was implemented using Grasshopper and models with different bone loss types and depths around a dental implant were built. The models were used in a finite element analysis (FEA) to predict the stresses in peri-implant bone.
View Article and Find Full Text PDFPlast Reconstr Surg Glob Open
April 2023
Unlabelled: The gracilis muscle flap is a popular choice in reconstructive surgery to repair soft tissue defects or for functional restoration. Little is known on the influence of postoperative application of VAC (vacuum-assisted closure; Kinetic Concepts Inc., San Antonio, Tex.
View Article and Find Full Text PDFThis study analyzed the fracture load before and after a chewing simulation of zirconia crowns that were trepanned and repaired using composite resin. Overall, 3 groups with 15 5Y-PSZ crowns in each group were tested. For group A, the fracture load of the unmodified crowns was evaluated.
View Article and Find Full Text PDFStatement Of Problem: How the fracture strength of recently introduced 3-dimensionally (3D) printed interim materials compares with that of conventional materials is unclear.
Purpose: The purpose of this in vitro study was to compare the fracture load of 4-unit interim fixed partial dentures made from 3 different materials before and after mastication simulation.
Material And Methods: Based on a master model of a 4-unit fixed partial denture with maxillary left first premolar and second molar abutment teeth, interim restorations were fabricated from 3 different materials (3D-printed, Temporary CB Resin, milled, PMMA for brain, and manually manufactured, Luxatemp Plus).
The aim of this study was to determine the effect of sandblasting, grinding and plasma treatment on the adhesive bond strength between framework ceramic (Y-TZP) and veneering ceramic (feldspar ceramic). Therefore, four-point bending specimens (n = 180) were cut from densely sintered 3Y-TZP blanks. Subsequently, 80 of these samples received surface treatment by sandblasting and 80 samples by grinding.
View Article and Find Full Text PDFThe aim of this study was to investigate abrasion on human dentin after brushing with activated charcoal toothpastes. A self-designed brushing machine was used to brush five groups (Group A: Water, Group B: Sensodyne Pro Schmelz, Group C: Splat Blackwood, Group D: Curaprox Black is White, and Group E: Prokudent Black Brilliant) with electrically powered toothbrushes for 4 h. The abrasive dentin wear was calculated using profilometry data.
View Article and Find Full Text PDFBiomedicines
January 2022
Cytokine profiles are often perturbed after infections of medical implants. With a non-invasive imaging system, we report in a mouse model that interferon expression after infection of subcutaneous implants with , , , and (alone or as a combination) was species-specific, persisted longer in the presence of implants, and notably decreased upon dual species infections. This type I interferon expression disappeared within two weeks; however, histology of implant-tissue interface indicated high recruitment of immune cells even after three weeks.
View Article and Find Full Text PDFThe present study reports on the long-term drug release and mechanical properties of bioactive dental filling materials based on chlorhexidine diacetate (CHX) or octinidine (di)hydrochloride (ODH) incorporated in a composite based on dimethacrylates or an ormocer. CHX or ODH were added to a nano-hybrid ormocer (O) and a nano-hybrid composite (C) with the amount of 2 wt% to achieve four matrix-drug combinations: O-CHX, O-ODH, C-CHX, and C-ODH. Drug extraction and release were measured using high-performance liquid chromatography with diode-array detection (HPLC-DAD), while drug distribution was assessed by using energy dispersive X-ray spectroscopy (EDX).
View Article and Find Full Text PDFWith the aim to design bioactive dental restorative material, the present study investigated the influence of the antimicrobial agents chlorhexidine diacetate (CHX) and octinidine (di)hydrochloride (ODH) when incorporated in two different materials. Selected parameters were polymerization enthalpy, short-term drug release, and the effect on Streptococcus mutans as well as human gingival fibroblasts. Samples were made by mixing a nano-hybrid ormocer (O) and a methacrylate-based nano-hybrid composite (C), each with a mass fraction of 2% CHX or ODH.
View Article and Find Full Text PDFObjectives: The purpose of this in vitro study was to compare the abrasion behaviour of different charcoal toothpastes when brushing with electric toothbrushes on human enamel.
Materials And Methods: A self-designed brushing machine was built using six commercially available electric toothbrushes in abrasion chambers. Each chamber was constantly supplied with a toothpaste-water mix.
The performance of biomaterials is often compromised by bacterial infections and subsequent inflammation. So far, the conventional analysis of inflammatory processes in vivo involves time-consuming histology and biochemical assays. The present study employed a mouse model where interferon beta (IFN-β) is monitored as a marker for non-invasive rapid detection of inflammation in implant-related infections.
View Article and Find Full Text PDFObjectives: This single-blinded randomized clinical trial evaluated the effect of adjuvant oral irrigation in addition to self-administered oral care on prevalence and severity of peri-implant mucositis.
Material & Methods: After randomization, patients suffering from peri-implant mucositis were assigned to the following: Group 1 (control) received oral hygiene instruction following a standardized protocol, including a sub- and supramucosal mechanical debridement. Group 2 and 3 additionally were instructed to use an oral irrigator with either water or 0.
Implant restoration is one of the basic treatments in dentistry today, yet implant loss from occlusal overload is still a problem. Complex biomechanical problems such as occlusal overload are often analyzed by means of the finite element method. This numerical method makes it possible to analyze in detail the influence that different loading situations have upon implants and tissues, which is a key element in optimizing these dental procedures.
View Article and Find Full Text PDFPurpose: To evaluate the load at fracture and influence of artificial aging of posterior teeth occlusal veneers ("table tops") made of two different ceramics.
Materials And Methods: A total of 80 table tops were produced from feldspathic ceramic (VM) and zirconia-reinforced lithium silicate ceramic (CD) using computer-aided design/computer-assisted manufacturing (CAD/CAM). Half of the specimens from each ceramic were aged prior to the load test.
Purpose: Fractures, occlusal adjustments, or marginal corrections after removing excess composite cements result in rough surfaces of all-ceramic FPDs. These have to be polished to prevent damage of the surrounding tissues. The aim of this study was to evaluate the roughness of zirconia, silicate-ceramic, and composite after polish with different systems for intraoral use.
View Article and Find Full Text PDFPurpose: Plasma activation of hydrophobic zirconia surfaces might be suitable to improve the bond strength of luting materials. The aim of this study was to analyze the influence of nonthermal argon-plasma on the shear bond strength (SBS) between zirconia and different combinations of 10-MDP adhesive systems and luting composites after artificial aging.
Materials And Methods: Two hundred forty Y-TZP specimens were ground automatically with 165 µm grit and water cooling.
Purpose: In literature, many studies compare survival rates of different types of FPDs. Most of them compared restorations, which originated from one university, but from different clinicians. Data about restoration survival rates by only one experienced dentist are very rare.
View Article and Find Full Text PDFPurpose: Temperature increase of 5.5 ℃ can cause damage or necrosis of the pulp. Increasing temperature can be caused not only by mechanical factors, e.
View Article and Find Full Text PDFComput Methods Biomech Biomed Engin
August 2017
In almost all finite element (FE) studies in dentistry, virtual forces are applied directly to dentures. The purpose of this study was to develop a FE model with non-linear contact simulation using an antagonist as force transmitter and to compare this with a similar model that uses direct force transmission. Furthermore, five contact situations were created in order to examine their influence on the peri-implant bone stresses, which are relevant to the survival rate of implants.
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