Publications by authors named "Einas Osman"
Background: Antibiotic resistance (ABR) is a major public health issue, associated with increased patient morbidity and mortality globally, with significantly higher rates in low- and middle-income countries (LMICs). Assessment of contextual factors, such as information, education, infrastructure and regulations are important for developing local solutions against ABR.
Objectives: To determine the knowledge and practices of healthcare workers (HCWs) towards ABR in hospitals in Sudan.
in Sudan: Multidrug Resistance, Polyclonal Dissemination, and Virulence.
Antibiotics (Basel)
January 2023
The emergence and global expansion of hyper-virulent and multidrug resistant (MDR) is an increasing healthcare threat worldwide. The epidemiology of MDR is under-characterized in many parts of the world, particularly Africa. In this study, isolates from hospitals in Khartoum, Sudan, have been whole-genome sequenced to investigate their molecular epidemiology, virulence, and resistome profiles.
View Article and Find Full Text PDFMolecular Epidemiology of Carbapenem-Resistant From Khartoum State, Sudan.
Front Microbiol
February 2021
Article Synopsis
- Carbapenem-resistant A. baumannii (CRAb) is a significant global health threat in hospitals, leading to higher rates of illness and death due to limited treatment options.
- Data from a study in four hospitals in Khartoum, Sudan, revealed that 42 multi-drug resistant (MDR) isolates were sequenced, highlighting their diverse antibiotic resistance mechanisms.
- The predominance of international clonal lineage IC2 (88%) among the isolates, along with some from IC1, IC5, and IC9, indicates a widespread issue with multiple resistance determinants in the region.
Multiclonal spread of Klebsiella pneumoniae across hospitals in Khartoum, Sudan.
J Glob Antimicrob Resist
March 2021
Article Synopsis
- * A total of 117 K. pneumoniae isolates were analyzed, revealing 52 different sequence types and confirming that all isolates were multidrug-resistant, with 37.6% classified as carbapenemase-producing K. pneumoniae.
- * The research indicates a widespread presence of drug-resistant K. pneumoniae in Khartoum, highlighting the urgent need for more systematic studies on drug-resistant infections to improve local healthcare strategies.
is recognized as one of the most important healthcare-associated pathogens worldwide due to its tendency to develop antibiotic resistance and cause fatal outcomes. Bacterial identification methods such as culture and biochemical tests are routinely used with limited accuracy in many low- and middle-income countries, including Sudan. The aim of this study was to test the accuracy of identification of in Khartoum, Sudan.
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