Publications by authors named "Einam Rahamim"
Background: Janus kinase-2 (JAK2) is mutated in a high proportion of patients with polycythemia vera and in a smaller number with essential thrombocythemia and primary myelofibrosis. Mutated JAK2 is an important diagnostic marker for myeloproliferative neoplasm (MPN) and may also play a major role in the pathogenesis of MPN.
Objectives: To evaluate the prevalence of mutated JAK2 (JAK2-V617F) among patients with major intraabdominal vein thrombosis who had normal blood counts at diagnosis of the initial event.
Article Synopsis
- Recent studies have suggested that gemtuzumab ozogamicin (GO) combined with cytarabine can improve outcomes for elderly patients with acute myeloid leukemia (AML), showing high response rates and manageable toxicity.
- In a 5-year study with 16 elderly patients, a complete remission rate of 68.8% was achieved, particularly in those with favorable or intermediate-I genetic profiles, while none in the poor-risk groups responded.
- The research emphasizes the importance of genetic risk stratification, revealing that median survival was significantly longer for those in the favorable and intermediate-I groups compared to their peers in the other risk categories.
Total and differential leukocyte counts percentiles in normal pregnancy.
Eur J Obstet Gynecol Reprod Biol
January 2008
Objective: To establish leukocyte count and leukocyte differential percentiles in normal uncomplicated pregnancy.
Study Design: This retrospective longitudinal study was performed in an outpatient facility for routine antenatal care. The study population comprised of 726 healthy women from the 5th to the 41st week of pregnancy.