Publications by authors named "Eiman M El-Saied"
The present study aims to investigate the ability of CaNa2EDTA (ethylenediaminetetraacetic acid) macroparticles and nanoparticles to treat cadmium-induced toxicity in female rats and to compare their efficacies. Forty rats were divided into 4 equal groups: control, cadmium, cadmium + CaNaEDTA macroparticles and Cd + CaNaEDTA nanoparticles. Cadmium was added to the drinking water in a concentration of 30 ppm for 10 weeks.
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- - The study explored the protective effects of zinc nanoparticles (Zn NPs) against brain damage caused by silver nanoparticles (Ag NPs) in male rats, focusing on oxidative stress and apoptosis.
- - Rats were divided into four groups and treated with Ag NPs, Zn NPs, or both over 12 weeks, leading to significant increases in oxidative damage markers and apoptosis-related gene expression in those exposed to Ag NPs alone.
- - Co-administration of Zn NPs alongside Ag NPs notably reduced neurotoxic effects, suggesting that Zn NPs could be an effective preventive treatment for Ag NPs-related brain damage.
Article Synopsis
- * Zinc nanoparticles (Zn-NPs) possess protective properties that mitigate the toxic effects caused by Ag-NPs when administered together, highlighting their antioxidative and anti-inflammatory benefits.
- * The study concludes that while Ag-NPs can harm organ function through mechanisms like apoptosis and oxidative stress, Zn-NPs can help counteract these adverse effects.
Introduction: Silver nanoparticles (Ag-NPs) are among the most commonly used nanoparticles in different fields. Zinc nanoparticles (Zn-NPs) are known for their antioxidant effect. This study was designed to investigate the adverse effects of Ag-NPs (50 nm) on the male reproductive system and also the ameliorative effect of Zn-NPs (100 nm) against these harmful effects.
View Article and Find Full Text PDFBackground And Aim: Chlorpyrifos (CPF) is a widely used organophosphate insecticide. Nanoparticles of zinc oxide (ZnO NPs) physically showed effective adsorbing property for some insecticides. The study was conducted to estimate the potential effect of ZnO NPs against CPF toxicity.
View Article and Find Full Text PDFIntroduction: AflatoxinB1 (AFB1) is well-known as a feed borne-hepatotoxic and immunosuppressive mycotoxin. This study was conducted to evaluate the efficacy of nanocomposite magnesium oxide and silicon oxide (MgO-SiO) in reducing the toxic effects of AFB1on the immunity and histological alterations in liver, spleen and intestine of adult male rats.
Experimental Design: Animals were divided into a control (Gp1) and three experimental groups (Gps); Gp2 received feed contained 200 ppb AFB1, Gp3 received feed contained 200 ppb AFB1 and 0.