Publications by authors named "Eiman M Abdul Rahman"
Influenza A viruses (IAVs) cause seasonal flu and occasionally pandemics. The current therapeutics against IAVs target two viral proteins - neuraminidase (NA) and M2 ion-channel protein. However, M2 ion channel inhibitors (amantadine and rimantadine) are no longer recommended by CDC for use due to the emergence of high level of antiviral resistance among the circulating influenza viruses, and resistant strains to NA inhibitors (oseltamivir and zanamivir) have also been reported.
View Article and Find Full Text PDFArticle Synopsis
- The study focused on improving the diagnosis of infective endocarditis (IE), especially cases that are hard to identify through traditional culture methods due to antibiotics or tricky microorganisms.
- Researchers included 156 patients, using blood cultures and serological tests for various pathogens, along with molecular techniques like PCR to analyze potential infection in blood and heart tissues.
- Their findings showed that while traditional blood cultures identified only 30.3% of cases, combining different diagnostic approaches reduced unidentifiable cases significantly from 69.7% to 49.2%, emphasizing the value of advanced serological and molecular methods in diagnosing IE.
Purpose: To compare polymerase chain reaction (PCR) to microbial culture and smear for detection and identification of bacterial and fungal pathogens in suspected microbial keratitis.
Materials And Methods: Corneal scrapings from 88 patients with suspected infectious keratitis were subjected to routine bacterial culture and sensitivity, Gram's stain, fungal culture; potassium hydroxide (KOH) wet mount, and PCR. PCR was performed with primer pairs targeted to the 16S and 18S r RNA gene.
Background: Infections caused by extended-spectrum β-lactamase (ESBL)-producing bacteria become an emerging problem in the community setting in many parts of the world.
Objective: The objective of the study was to determine fecal carriage of ESBL-producing organisms in a community setting.
Methods: A total of 632 fecal specimens from healthy individuals were screened for ESBL using the agar screening test with MacConkey agar plates supplemented with 1 μg/mL of cefotaxime for selection of ESBL-producing strains and confirmed by the Clinical Laboratory Standards Institute combined disk method.