Publications by authors named "Eileen K Koch"

Aims: Vertebral bone marrow is a rich and easily accessible source of hematopoietic and mesenchymal stem cells that has been used to promote chimerism and transplantation tolerance in connection with cadaveric organ transplantation. The purpose of this study is to provide a detailed account of the procedure used to prepare the first five vertebral bone marrow products for infusion in conjunction with the first hand/hand-forelimb transplants performed at the University of Pittsburgh (PA, USA).

Materials & Methods: The cell separation and release testing were performed at the University of Pittsburgh Cancer Institute's Hematopoietic Stem Cell Laboratory, a Good Manufacturing Practice-compliant facility accredited for clinical cell processing by the Foundation for Accreditation of Cellular Therapy (FACT) and for clinical flow cytometry by the College of American Pathologists (CAP).

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Synopsis of recent research by authors named "Eileen K Koch"

  • - Eileen K Koch's recent research investigates the clinical implementation of a procedure to prepare bone marrow cells from cadaveric vertebral bodies for use in transplantation procedures.
  • - The study highlights the extraction of hematopoietic and mesenchymal stem cells from vertebral bone marrow, emphasizing their potential in promoting chimerism and transplantation tolerance in organ transplants.
  • - Conducted at the University of Pittsburgh, the research ensures rigorous compliance with Good Manufacturing Practices and accreditation standards for clinical cell processing and flow cytometry, indicating the study's commitment to high-quality research methodologies.