Myocardial density analysis utilizing automated myocardial defect analysis software on resting 320-detector MDCT.

Cardiac CT myocardial perfusion is an emerging tool utilizing differences in myocardial density of ischemic compared to normal myocardium. We sought to document the contrast enhanced density profile of myocardial segments subtended by severely stenotic coronary arteries on rest (non stress) cardiac CT imaging, and compare the density with identical segments without ischemic disease. 100 cardiac CT studies were identified resulting in 25 normal patients, 37 with severe left anterior descending artery stenosis, 14 with severe left circumflex artery stenosis, and 24 with severe right coronary artery stenosis.