A comparison of the incidence of ≥ grade 2 radiation pneumonitis between intensity-modulated radiotherapy and three-dimensional conformal radiotherapy in patients with unresectable non-small cell lung cancer treated with durvalumab after concurrent chemoradiotherapy.

Background: Intensity-modulated radiation therapy (IMRT) has been increasingly used as a new radiation modality for unresectable non-small cell lung cancer (NSCLC). The risk factors for radiation pneumonitis (RP) during consolidation durvalumab following concurrent chemoradiotherapy (CCRT) using IMRT have not been thoroughly investigated.

Methods: This retrospective study analyzed medical record data from consecutive patients diagnosed with NSCLC who underwent CCRT and consolidation durvalumab at our institution between April 2018 and September 2022.

The application of a radiotherapy-planning system: consideration from a case of intraoral squamous cell carcinoma that lacked a control.

Objective: The purpose of this case study was to present an applied example of a radiotherapy-planning system used during the treatment of a malignant tumor in the oral and maxillofacial region.

Study Design: The various radiotherapy modalities were performed on a patient with oral squamous cell carcinoma of multiple metachronous recurrences. Estimated radiation dose-distribution curves for each radiotherapy modality were computed by using a commercially available radiotherapy-planning system.