Prevention of the exposure by cyclophosphamide oral tablet.

Background: Unintended exposure to antitumor agents from an oral medicine may place healthcare workers and patients taking medicine at risk. In this study, the exposure to blister pack by CP (cyclophosphamide) and appropriate preventive procedures were examined.

Findings: CP detected inside the blister pack of the tested seven lots by LC-MS/MS ranged from 8.

Effects of boiling on the antihypertensive and antioxidant activities of onion.

This study was designed to show the effect of boiling on the antihypertensive and antioxidant activities of onion in N(G)-nitro-L-arginine methyl ester (L-NAME) induced-hypertensive rats and spontaneously hypertensive rats (SHR). Male 6-wk-old Sprague-Dawley rats were made hypertensive by being given distilled water containing L-NAME at a dose of 50 mg/kg BW/d. These rats were fed diets containing raw or boiled onion at a concentration of 5%.