Publications by authors named "Eiji Saegusa"
Objective The long-term impact of personalized diet and exercise programs for steatotic liver disease (SLD) remains unclear. Materials The subjects of this retrospective cohort study included 104 consecutive Japanese patients with SLD. The long-term treatment efficacy of personalized diet and exercise treatment was evaluated two years after the start of observation.
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- The study examined the impact of personalized diet and exercise on patients with steatotic liver disease (SLD), focusing on how genetic differences might affect treatment outcomes.
- Conducted with 203 Japanese patients, the program included specific caloric intake and exercise routines over six months, leading to significant improvements in liver function tests and metabolic markers.
- Although treatment generally benefited all participants, certain genetic variants (like TM6SF2 and HSD17B13) did show varying rates of improvement, suggesting that future personalized programs should consider these genetic factors.
Article Synopsis
- A study evaluated the effectiveness of a combined diet and exercise program for patients with fatty liver, particularly nonalcoholic fatty liver disease (NAFLD), using 186 Japanese subjects.
- Patients in the hospitalization group (153 cases) showed a significantly greater improvement in liver function tests and body weight over 6 months compared to those not hospitalized (33 cases).
- Factors such as the cause of fatty liver, diabetes presence, and larger waist circumference were identified as independent predictors of improved blood sugar levels in those undergoing the program.