Publications by authors named "Eiji Katayama"

Article Synopsis
  • - The study focuses on improving the diagnosis of primary central nervous system lymphoma (PCNSL) during surgery by using intraoperative rapid immunohistochemistry (IHC), along with cytology and flow cytometry (FCM) for quicker and more accurate treatment decisions.
  • - In a trial involving 35 patients from April 2020 to January 2024, the addition of cytology and FCM to rapid IHC significantly sped up the time from surgery to chemotherapy initiation for PCNSL (1.6 days versus 7.3 days), demonstrating the benefits of this combined approach.
  • - Final pathological diagnoses confirmed the consistency of intraoperative rapid IHC results, and the combined method resulted in changes in treatment strategy in certain
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In the treatment of primary central nervous system lymphoma (PCNSL), intraoperative rapid pathological diagnosis can dramatically change the surgical strategy, and more accurate diagnostic methods are required. In April 2020, we adopted intraoperative rapid immunohistochemistry (IHC) in addition to conventional rapid intraoperative diagnosis based on morphological assessment, mainly for patients with PCNSL. Here, we investigate the usefulness and significance of intraoperative rapid IHC based on our initial experience.

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A turnover number (TON) of 2 400 000 and a turnover frequency (TOF) of 63 s are achieved with the chiral Ru complex 1 (R=p-CH C H ) in the asymmetric hydrogenation of acetophenone. Carbonyl-selective asymmetric hydrogenation of α,β-unsaturated ketones proceeds in the presence of these Ru catalysts, and 4-substituted cyclohexanones are selectively converted into cis alcohols.

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