Publications by authors named "Eiichi Nishimura"

Background: Intraocular lens (IOL) fixation is performed after intraoperative anterior or total vitrectomy. This study aimed to compare the intraoperative and postoperative complications of these two techniques.

Methods: This retrospective study included 235 eyes that underwent intrascleral fixation surgery at our hospital between July 2014 and January 2021.

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Purpose: To report the intermediate-term results of capsule stabilization for scleral fixation with implantation of the Yaguchi hook, a modified capsule expander stabilization hook.

Setting: Department of Ophthalmology, School of Medicine, University of Showa, Fujigaoka Rehabilitation Hospital, Yokohama, Japan.

Design: Retrospective case series.

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Loss of barrier integrity precedes the development of pathologies such as metastasis, inflammatory disorders, and blood-retinal barrier breakdown present in neovascular age-related macular degeneration. Rap1 GTPase is involved in regulating both endothelial and epithelial cell junctions; the specific role of Rap1A vs. Rap1B isoforms is less clear.

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Background: It is not rare to meet unilateral nuclear sclerotic cataracts with myopic refractive changes (lenticular myopia) compared with the fellow eye in the ophthalmic examination of patients with decreased visual acuity. To determine the relationship between the myopic refractive changes and interocular differences of parameters, we investigated the interocular differences of ocular parameters between a lenticular myopic eye and the fellow eye.

Method: This retrospective study included 68 eyes of 34 patients, who showed unilateral lenticular myopia.

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Diabetes can lead to serious microvascular complications including proliferative diabetic retinopathy (PDR), the leading cause of blindness in adults. Recent studies using gene array technology have attempted to apply a hypothesis-generating approach to elucidate the pathogenesis of PDR, but these studies rely on mRNA differences, which may or may not be related to significant biological processes. To better understand the basic mechanisms of PDR and to identify potential new biomarkers, we performed shotgun liquid chromatography (LC)/tandem mass spectrometry (MS/MS) analysis on pooled protein extracts from neovascular membranes obtained from PDR specimens and compared the results with those from non-vascular epiretinal membrane (ERM) specimens.

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Purpose: To evaluate the detrition of clear corneal incisions (CCIs) after intraocular lens (IOL) implantation using an injector system in porcine eyes.

Methods: Group A: after CCIs were performed with 1.8, 2.

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We describe a new capsular stabilization device for suspending a lens with weak zonular support. It is flexible, 10.0 mm in length, and fashioned from 5-0 nylon.

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Purpose: To compare lens epithelial cell migration between intraocular lens (IOL) optics and the posterior capsule of IOLs with various edges and haptic angulations.

Methods: Experimental acrylic IOLs with 3 types of finishing (none, polishing, tumbling and polishing) and 2 types of haptic angulation (10 and 15 degrees ) as well as 3 (AcrySof MA30BA, Sensar AR40, CeeOn 911) clinically implanted IOLs were inserted in rabbit eyes. Scanning electron-microscopic examination of IOLs was carried out before surgery and histological examination of lens capsules 3 weeks after surgery.

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