Background: COVID-19-related social restrictions provided an opportunity to evaluate the impact of social isolation on Parkinson's disease.
Objective: This study aimed to explore changes in social isolation and their associations with PD symptoms using the Lubben Social Network Scale-Revised (LSNS-R).
Methods: Data from 80 participants of the Early Parkinson's Disease Longitudinal Singapore cohort were collected from April 2019 to April 2023, covering the periods before and after the imposition of COVID-19 restrictions.