CONSTRUCTION AND VALIDATION OF IN VITRO DOSE-RESPONSE CALIBRATION CURVE USING DICENTRIC CHROMOSOME ABERRATION.

Cytogenetic biodosimetry is a well-known method for quantifying the absorbed dose based on measuring biological radiation effects. To correlate the induced chromosomal abberrations with the absorbed dose of the individuals, a reliable dose-response calibration curve should be established. This study aimed to use frequencies and distributions of radiation-induced dicentric chromosome aberrations to develop a standard dose-response calibration curve.

Calculation of water equivalent ratio of several dosimetric materials in proton therapy using FLUKA code and SRIM program.

Water equivalent ratio (WER) was calculated for different proton energies in polymethyl methacrylate (PMMA), polystyrene (PS) and aluminum (Al) using FLUKA and SRIM codes. The results were compared with analytical, experimental and simulated SEICS code data obtained from the literature. The biggest difference between the codes was 3.