Publications by authors named "Ehsan Ghamarian"
Article Synopsis
- Patient reported outcomes (PROs) are vital for assessing health-related quality of life in adult patients with congenital heart disease, but they are not well defined for this population.
- This study aimed to evaluate how well different PRO survey tools could distinguish between patients with Fontan circulatory failure (FCF) and those with simpler shunt lesions.
- The Kansas City Cardiomyopathy Questionnaire (KCCQ-12) showed the best ability to identify FCF, and combining it with other PRO tools further improved its effectiveness, suggesting that these measures can help inform management strategies for adult congenital heart disease patients.
Aim: We sought to describe the impact of the COVID-19 pandemic on the care provided by Canadian emergency medical system (EMS) clinicians to patients suffering out of hospital cardiac arrest (OHCA), and whether any observed changes persisted beyond the initial phase of the pandemic.
Methods: We analysed cases of adult, non-traumatic, OHCA from the Canadian Resuscitation Outcome Consortium (CanROC) registry who were treated between January 27th, 2018, and December 31st, 2021. We used adjusted regression models and interrupted time series analysis to examine the impact of the COVID-19 pandemic (January 27th, 2020 - December 31st, 2021)on the care provided to patients with OHCA by EMS clinicians.
Background: Among critically ill patients with acute kidney injury (AKI), earlier initiation of renal replacement therapy (RRT) may mitigate fluid accumulation and confer better outcomes among individuals with greater fluid overload at randomization.
Methods: We conducted a pre-planned post hoc analysis of the STandard versus Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial. We evaluated the effect of accelerated RRT initiation on cumulative fluid balance over the course of 14 days following randomization using mixed models after censoring for death and ICU discharge.