Publications by authors named "Ehab Saleh"
Article Synopsis
- - Obesity increases the chance of wound complications after total knee arthroplasty (TKA), prompting researchers to examine fat content in preoperative CT images as a potential predictor for these complications.
- - In a study involving 150 patients, measurements of subcutaneous fat (SCF) at specific knee locations showed that both the lowest and highest levels of SCF were linked to a higher rate of wound complications compared to moderate amounts.
- - Results indicate that moderate levels of periarticular fat are associated with better postoperative outcomes, highlighting the importance of fat measurement in evaluating surgical risks for TKA patients.
Objectives: The COVID-19 pandemic has had a profound effect on the pediatric population worldwide. The consequences of the lockdown and the reallocation of hospital resources have caused notable changes in the presentation of pediatric orthopedic injuries. Through our use of patient records, we were able to display the epidemiological trends, as well as analyze the changes in the type and mechanism of various injuries.
View Article and Find Full Text PDFArticle Synopsis
- The NFL is immensely popular in the U.S., drawing many hopeful athletes, but pursuing a career in it poses serious health risks, especially concussions and conditions like CTE.
- Evidence suggests repeated head injuries can lead to long-term neurodegenerative diseases, yet NFL officials have often minimized the link between concussions and CTE, blaming other factors.
- To combat this issue, the NFL has made some changes like safer helmets, but more effective solutions like early detection via MRI scans and innovative therapies are needed to address the health crisis and protect players.
Operative Management of Pediatric Physeal Bar Development and Genu Valgum.
Orthop Rev (Pavia)
August 2024
Article Synopsis
- Pediatric orthopedic issues can be complicated because children's bones are still growing, which requires special attention to both structural and functional problems.
- A case involving a 13-year-old with recurring knee pain related to an early childhood infection resulted in surgery to correct growth-related knee deformities.
- The successful surgical treatment emphasized the need for comprehensive rehabilitation to strengthen muscles and prevent further complications, showcasing the value of teamwork in managing these cases.
Background: The purpose of this study was to assess if subcutaneous fat (SCF) or BMI is a predictor of surgical complications and patient reported outcomes in patients undergoing robotic-assisted total hip arthroplasty (THA).
Methods: Patients who underwent robotic-assisted primary THAs at one institution between 2018 and 2020 were included in this retrospective cohort study. Prior to surgery, computed tomography (CT) was used to measure SCF in the posterolateral quadrant of the hip.
Article Synopsis
- - Longitudinal bone growth is influenced by various factors, including nutrients and hormones, but childhood obesity can disrupt these processes by affecting signaling pathways and placing stress on the body.
- - A review of existing research highlights the role of the epiphyseal growth plate and shows how obesity leads to abnormal bone development, emphasizing the need for adequate nutrition during critical growth periods.
- - To promote healthy bone growth, the review suggests focusing on nutrient-dense diets rather than caloric restrictions, and that supervised weight loss with proper nutrition can mitigate the negative impacts of childhood obesity on bone health.
Article Synopsis
- The study evaluated the effectiveness of two nailing systems—Titanium Elastic Nailing (TENS) and Stainless Steel Elastic Nailing (SSENS)—for treating pediatric femoral fractures in patients aged 6 to 16 years.
- Data from 83 patients treated at William Beaumont Hospital revealed similar outcomes between TENS and SSENS, with TENS taking an average of 93.8 days for fracture union and SSENS taking 82.2 days.
- The findings indicate no significant differences in complications or recovery times between the two methods, suggesting the choice of nailing system should depend on individual patient circumstances, though the study faced limitations such as a small sample size.
#lowbackpain on TikTok: A New Frontier for Orthopaedic Medical Education.
J Am Acad Orthop Surg Glob Res Rev
April 2024
Introduction: Low back pain has become a substantial health problem in all developed countries. Many healthcare professionals and content creators have begun sharing their treatment methods and opinions through social media, especially the video-based platform TikTok. TikTok has been downloaded more than 2.
View Article and Find Full Text PDFThe purpose of this study was to determine if short-term outcomes differed for pediatric patients with suspected musculoskeletal infection with or without a preoperative MRI. This was a multicenter, retrospective review of patients aged 0-16 years who presented with atraumatic extremity pain, underwent irrigation and debridement (I&D), and received at least one preoperative or postoperative MRI over a 10-year period. Primary outcomes were time to OR, total I&Ds, readmission rate, time from OR to discharge, and total number of MRIs.
View Article and Find Full Text PDFArticle Synopsis
- * Initially treated with a fracture brace, she showed no healing after eight weeks and continued conservative management until she returned four months later with persistent motion at the fracture site.
- * The patient eventually underwent surgery for nonunion with open reduction, internal fixation, and bone grafting, resulting in successful healing, indicating that adult treatment methods can be effective for pediatric cases despite their rarity.
Cyclosporine (CsA) is a potent immunosuppressant agent that has been used since 1980 for the treatment of various autoimmune diseases and is extensively used to enhance the survival rate of patients and grafts following organ transplant surgeries. CsA is a poorly soluble drug with a narrow therapeutic window and inter-subject variability, which can lead to graft rejection, nephrotoxicity and other severe adverse effects. This study explores a novel method that combines solubility enhancement of CsA using SNEDDS formulation and personalized dosage delivery using 3D printing technology.
View Article and Find Full Text PDFStudy Design: Systematic Review.
Objectives: To determine the efficacy and overall outcomes of iFactor/ABM/P-15 following lumbar spine surgery.
Methods: We performed a search of the Cochrane Library, Medline Ovid, PubMed, and SCOPUS databases from inception until August 2023.
Article Synopsis
- The study aimed to determine how the duration of symptoms before lumbar microdiscectomy impacts recovery outcomes, including pain relief and return to work.
- Researchers analyzed data from 2408 patients categorized into three groups based on the length of time they experienced symptoms before surgery: under 3 months, 3 months to 1 year, and over 1 year.
- Results showed that patients who had surgery within 3 months of symptom onset had significantly better pain relief and overall functional improvement compared to those with longer symptom durations.
Article Synopsis
- VR and AR technologies are revolutionizing spinal surgery by providing immersive training for trainees and enhancing precision for experienced surgeons.
- Despite their potential, challenges like high costs and integration issues hinder widespread adoption.
- The article discusses the importance of validating these technologies and conducting cost-benefit analyses to understand their future impact in healthcare.
Article Synopsis
- * These technologies bring increased precision and personalization to surgeries, leading to better patient outcomes.
- * The editorial discusses surgeons' changing views on AI and robotics, highlighting their benefits, limitations, and future possibilities based on recent research findings.
Pediatric Distal Tibia Physeal Injury Presenting with Acute In-toeing: A Case Report and Literature Review.
J Am Acad Orthop Surg Glob Res Rev
August 2023
Ankle fractures are among the most common fractures sustained in the pediatric population. Given the frequency of physeal involvement of the distal fragment, complications including growth arrest, overgrowth, and rotational deformities are not uncommon. This case report describes a 12-year-old adolescent boy who presented after an acute right ankle injury sustained while playing.
View Article and Find Full Text PDFArticle Synopsis
- Unicompartmental knee arthroplasties (UKAs) were performed on 56 patients using a minimally invasive method, with 62 surgeries reviewed over a follow-up period of 2.5 years.
- Of the 62 UKAs, 11% experienced subsidence in the medial tibial components, leading to pain and the need for some revisions to total knee arthroplasties.
- The study highlights a significant rate of complications, including deep vein thrombosis and infections, indicating that unicompartmental surgeries still carry risks similar to total knee arthroplasties.
Article Synopsis
- * A study analyzed 12 cases over five years, revealing that most patients (average age 53) had ganglion cysts, with the surgical removal consistently performed from the dorsal side.
- * Due to the complexity of the anatomy and variety of potential diagnoses, thorough preoperative planning and advanced imaging are essential for effective surgery.
A Tibial Tubercle Fracture Masquerading as an Inferior Pole of the Patella Fracture.
J Am Acad Orthop Surg Glob Res Rev
January 2023
Pediatric tibial tubercle fractures are uncommon injuries that most often occur in adolescent men. Patients will typically present with anterior knee pain with or without patella alta. This case report describes a tibial tubercle fracture in a 13-year-old man misidentified as an inferior pole patella sleeve fracture on physical examination and preoperative radiographs.
View Article and Find Full Text PDFArticle Synopsis
- Monteggia fracture-dislocations are uncommon injuries in children, typically involving a fracture of the proximal ulna alongside dislocations in nearby joints, representing less than 1% of pediatric forearm fractures.
- A case study of a 6-year-old girl revealed a complex variant involving multiple dislocations and fractures following a fall, which required surgical intervention after unsuccessful attempts to realign the joints non-surgically.
- The surgical procedure involved repairing the ulna fracture and successfully stabilizing the dislocations, ultimately leading to a promising recovery after a period of immobilization in a cast.
Article Synopsis
- The study focuses on traumatic upper cervical spine injuries (tUCSI) in pediatric patients, analyzing trends in injury causes, treatment options, and patient outcomes within this group.
- Conducted over a decade at a Midwest trauma center, the study included 40 patients aged 1 day to 16 years, using various statistical tests to evaluate differences among three age groups.
- Findings revealed that motor vehicle collisions were the leading cause of tUCSI, with young children predominantly affected by falls, while sports injuries were more common in adolescents and juveniles.
Article Synopsis
- Flexible intramedullary nails (FNs) are effective for treating midshaft pediatric forearm fractures but can be challenging for distal fractures, prompting this study to analyze outcomes based on fracture location.
- A review of 59 pediatric patients treated with FNs from 2009 to 2018 showed that 81% achieved successful fixation, although some distal fractures required alternative fixation methods due to inadequate stabilization.
- The findings suggest most pediatric forearm fractures can be treated with FNs, but special attention is needed for distal fractures where fixation challenges are more common.
Article Synopsis
- * Diagnosis typically relies on clinical history, exams, lab tests, and imaging, but conditions that look like infections may require more invasive procedures like biopsies.
- * While many spinal infections in children can be treated with antibiotics, some severe cases need surgical intervention, emphasizing the importance of quick and accurate diagnosis for effective treatment.
Pediatric Calcaneal Tuberosity Avulsion Fracture: A Case Report and Literature Review.
J Orthop Case Rep
March 2021
Article Synopsis
- - Calcaneus fractures are uncommon in children, with avulsion fractures of the calcaneal tuberosity being even rarer, and require urgent treatment to avoid severe skin and soft tissue issues.
- - A case study of a 9-year-old girl who sustained a displaced calcaneal tuberosity fracture during a gymnastic fall is presented, noting her history of acute lymphoblastic leukemia in remission at the time.
- - Timely intervention is critical for pediatric calcaneal tuberosity fractures to prevent serious complications, emphasizing the need for prompt medical action.
The 3D printing techniques have been explored extensively in recent years for pharmaceutical manufacturing and drug delivery applications. The current investigation aims to explore 3D printing for the design and development of a nanomedicine-based oral solid dosage form of a poorly water-soluble drug. A self-nanoemulsifying tablet formulation of dapagliflozin propanediol monohydrate was developed utilizing the semisolid pressure-assisted microsyringe (PAM) extrusion-based 3D printing technique.
View Article and Find Full Text PDF