Publications by authors named "Ehab Mohamed Farag"
The world urgently requires surrogate markers to diagnose COVID-19 and predict its progression. The severity is not easily predicted via currently used biomarkers. Critical COVID-19 patients need to be screened for hyperinflammation to improve mortality but expensive cytokine measurement is not routinely conducted in most laboratories.
View Article and Find Full Text PDFDeep Hypothermic Circulatory Arrest in the Pediatric Population Undergoing Cardiac Surgery With Electroencephalography Monitoring: A Systematic Review and Meta-Analysis.
J Cardiothorac Vasc Anesth
October 2021
Article Synopsis
- Prolonged deep hypothermic circulatory arrest (DHCA) during cardiac surgery in children can pose risks to brain health, as suggested by increased seizure rates and neurological issues.
- A systematic review of 19 studies involving 1,267 pediatric patients found clinical seizure rates at 12.9% and EEG seizure rates at 14.9%, with a mortality rate of 6.3%.
- The findings indicate that longer DHCA durations correlate with a higher likelihood of EEG seizures and neurological abnormalities, which may contribute to neurodevelopmental delays.
Background: Magnesium was reported to reduce both the anesthetic requirements and the period needed to reach a bi-spectral index value of 60 when used intra-operatively (Br J Anaesth 83:302-20, 1999; Anesth Analg 20:1273-5, 1988; Br J Anaesth 89:594-8, 2002; Anesth Analg 87:206-10, 1998; Br J Anaesth 89:594-8, 2002; Br J Anaesth 94:438-41, 2005) and to minimize the emergence agitation (Anaesthesia 61:1058-63, 2006). Previous studies examined the influence of magnesium on the anesthetic requirements while the bi-spectral Index values were kept within a constant range. We evaluated the effect of intraoperative magnesium on the bi-spectral index values during pediatric anesthesia while we kept other anesthetic variables unchanged.
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