[The analysis of human resources of medical workers by profile "Stomatology" providing out-patient medical care to population of megalopolis within the framework of mandatory medical insurance].

The statistical report for 2017-2020 demonstrated that in outpatient conditions of multidisciplinary dental clinic providing services under compulsory medical insurance of population of megalopolis, there is increase in the number of physicians of the analyzed profile up to 304.5% and paramedical personnel up to 256.3% at the expense of young personnel.

Amorphization and nanocrystal formation in a Pd-Ni-Cu-P alloy after cooling under different conditions.

Structure formation during solidification of a Pd-Ni-Cu-P melt is studied. It is demonstrated that changes in the heat transfer conditions lead to a nonlinear change in the characteristics of the structure. The article presents the regimes of cooling the samples and the results of their structure and composition studies.

A cocrystal of L-ascorbic acid with picolinic acid: the role of O-H...O, N-H...O and C-H...O hydrogen bonds and L-ascorbic acid conformation in structure stabilization.

A new 1:1 cocrystal (L-Asc-Pic) of L-ascorbic acid (vitamin C) with picolinic acid was prepared as a powder and as single crystals. The crystal structure was solved and refined from single-crystal X-ray diffraction (SCXRD) data collected at 293 (2) and 100 (2) K. The samples of the L-Asc-Pic cocrystal were characterized by elemental (HCNS) analysis and titrimetric methods, TG/DTG/DSC, and IR and Raman spectroscopy.

[Modern approaches to the use of neurotropic physical therapy in arterial hypertension].

The development and introduction into clinical practice of non-pharmacological methods for the prevention and treatment of arterial hypertension is a primary objective of modern physical therapy, especially as regards the neurotropic influences. This article was designed to report the results of the investigation into the hypotensive effect of transcerebral magnetic therapy obtained during the treatment of 60 patients presenting with arterial hypertension. The study included the comparative examination of two randomly formed groups containing 30 patients each.

Functional state of sportsmen with mitral valve prolapse.

The study covered functional peculiarities in 541 professional sportsmen. Mitral valve prolapse (in 132 examinees) appeared to be associated with reliably lower levels of reticulocytes, leucocytes, lymphocytes CD4+, immunoglobulines G, magnesium, and higher cortisol level, in comparison with the sportsmen having no mitral valve prolapse. The athletes with mitral valve prolapse demonstrated more frequent changes in ECG, reliably lower performance in treadmill test, slower recovery of heart rate after exertion is over.

Optimization of therapeutic teaching of patients with chronic cardiac failure.

The study was aimed to evaluate treatment efficiency of patients with chronic cardiac failure via therapeutic teaching. The study included 137 patients. Implementation of therapeutic teaching into treatment of chronic cardiac failure patients resulted in less number of patients with III-functional grade, better tolerance to physical exertion, more awareness, greater number of patients with self-control skills and adherence to recommended treatment, better life quality of the patients.

[Use of adaptogens for antioxidant system correction in complex treatment of mandibular fractures].

Antioxidatic protection has been studied in 84 patients with mandibular fractures between the ages of 21 and 40; the patients were divided into two groups. Activation of lipid peroxidation in both groups was revealed. The increase of antioxidant's activity system in 37.

The impact of ultra-low amounts of amino-modified MMT on dynamics and properties of densely cross-linked cyanate ester resins.

Abstract: Thermostable nanocomposites based on densely cross-linked cyanate ester resins (CER), derived from bisphenol E and doped by 0.01 to 5 wt. % amino-functionalized 2D montmorillonite (MMT) nanoparticles, were synthesized and characterized using Fourier transform infrared (FTIR), transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDXS), wide-angle X-ray diffraction (WAXD), dynamic mechanical analysis (DMA), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), far-infrared (Far-IR), and creep rate spectroscopy (CRS) techniques.

[Social and hygienic aspects of mandible fractures in Republic of Sakha (Yakutia)].

Comprehensive social and hygienic survey of 209 patients with mandible fracture was conducted. Their social features were: young adults, predominantly male, ethnicity mainly yakuts, temporarily unemployed, with secondary and post-secondary education and health behavior problems. The majority of jaw injuries were caused by household (26.

[Evaluation of vascular modification in hypertensive patients].

Assessment of arterial stiffness for revealing vascular modification in hypertensive patients seems to be an actual problem in clinical practice. 377 patients with arterial hypertension and 232 nonhypertensive subjects were included in the research. The noninvasive technique of investigation of pulse wave velocity (PWV) was used.

[Programs for better health of individuals exposed to increased occupational risk].

The article deals with problems of optimizing sanatorium-and-spa programs to better health in workers exposed to vibration, through using panto-magnesium pearl baths. Examinations covered 49 individuals exposed to local vibration at work, who underwent health programs including magnetotherapy, manual massage and exercise therapy. The authors conclude that maximal effect of improved life quality was seen after panto-magnesium gas baths course auxiliary to the programs.

Well-defined oxide core-polymer shell nanoparticles: interfacial interactions, peculiar dynamics, and transitions in polymer nanolayers.

Interfacial interactions, chain dynamics, and glass and melting transitions were studied in well-defined core-shell nanoparticles with amorphous silica or crystalline alumina cores and noncrystallizable poly(vinyl pyrrolidone) (PVP) or crystallizable poly(ethylene glycol) (PEG) shells. Varying particle composition caused regular changes in the shell thickness from 1 to 2 nm (monomolecular layer) up to 90 nm. Far- and mid-IR spectroscopy allowed us to register hydrogen bonding and, tentatively, Lewis/Brønsted (LB) interfacial interactions as well as changes in the dynamics and conformational state of the polymer chains as a function of the nanoshell thickness.

Kindling in the early postnatal period: Effects on the dynamics of age-related changes in electrophysiological characteristics of hippocampal neurons.

The effects of chronic administration of pentylenetetrazole (PTZ) during early ontogenesis (from postnatal day 14) on the dynamics of age-related changes in electrophysiological characteristics of rat hippocampal slices were studied. Unlike the situation in adult animals, convulsive activity did not develop in rat pups in response to repeated injections. Comparison of the amplitude characteristics of total monosynaptic responses of neurons in hippocampal field CA1 to application of single and paired (separated by 70 msec) stimulation of Schäffer collaterals during the period of maximally intense hippocampal synaptogenesis (at weeks 2-3 of postnatal development) revealed no significant differences between the control group (administration of isotonic saline) and the group given PTZ.

[Kindling during early postnatal development: the effects on the maturation of the hippocampal electrophysiological characteristics].

The effect of repeated pentylentetrazole (PTZ) administration on the postnatal development of hippocampal electrophysiological indices has been studied. Contrary to adult rats, repeated PTZ injections did not intensify convulsive activity in rat pups (from postnatal day 14). We did not observe any between-group differences in population spike amplitudes and paired pulse facilitation (PPF) ratio at 70 ms interpulse interval during early period of postnatal development, PPF suppression at short interlulse interval (15 ms) only was significantly less in PTZ group as compared with saline-injected controls, but the effect of saline injections has developed in the same directio However PTZ resulted in the modification of developmental profile.

Analysis of cyclic adenosine-3',5'-monophosphate levels in structures of the "informational" and "motivational" systems of the rat brain during acquisition of a conditioned active avoidance reaction.

Cyclic adenosine-3'5'-monophosphate (cAMP) levels in structures of the "informational" and "motivational" systems of the brain were measured during acquisition of a conditioned two-sided active avoidance reflex in rats. cAMP levels were measured in three groups of animals--intact animals, trained animals, and an active control group (given uncombined presentations of the conditioned (light) and unconditioned (electric shock) stimuli)--immediately after reproduction of the acquired reflex. Significant accumulation of cAMP levels in brain structures was seen in animals of the active control group in the hypothalamus and in trained animals in the left and right hippocampus and the right frontal cortex.

[Analysis of the level of cyclic adenosine-3',5'-monophosphate in structures of the 'informational' and 'motivational' system of the rat brain during active conditioning].

The content of cyclic adenosine-3',5'-monophosphate (cAMP) was studied in structures of the "motivational" and "infromational" systems of rat brain after the active avoidance conditioning procedure in rats. Three groups of animals were examined: naive rats, trained (conditioned) rats, and group of the active control presented with uncombined conditioned (light) and unconditioned (electric footshock) stimuli. The content of cAMP was determined in the frontal cortex, hippocampus, amygdala, and hypothalamus of both hemispheres immediately after the retrieval of conditioned reaction one day after conditioning.

[Laser therapy of elderly patients with pneumonia].

The aim of the study was to evaluate the efficiency of laser therapy included into the treatment of pneumonia in the elderly. A follow-up included the analysis of their clinical status and external respiratory function, pulmonary blood flow, and immunological parameters in 2 matched groups of pneumonia patients aged 60 to 72 years. Low-intensity laser therapy (transcutaneous sliding contact procedure) was used as part of routine treatment in one of the groups.

[Effectiveness of prestarium in the treatment of chronic cor pulmonale].

Aim: To study efficiency and safety of application of perindopril (prestarium) in patients with chronic cor pulmonale (CCP).

Material And Methods: The trial included 26 patients with chronic obstructive pulmonary disease complicated with CCP and cardiac failure of NYHA class II-III. The study group of 16 patients received perindopril 2-4 mg/day for 3 months.

[Results of the use of pumpan preparation in the treatment of severe forms of angina pectoris].

Aim: To assess validity of adjuvant use of pumpan, a homeopathic compound, in patients with unstable angina pectoris and angina of effort (functional class III-IV) receiving conventional treatment.

Material And Methods: A direct open controlled trial for 15 months performed initially in hospital, then outpatiently, covered 49 patients with severe angina. Examination of the patients included evaluation of clinical condition and the disease course, lipid metabolism, hemostasis, blood plasma electrolytes, aminotransferases, echo-CG, bicycle exercise, rheoencephalography, ultrasonic dopplerography of head and neck vessels.

[Effect of the sciatic nerve blockade on the function of the contralateral motor center in the rat gastrocnemius muscle].

When the rat spinal motor centre was activated by fixing the animal in a supine posture, the motor units of intact gastrocnemius muscle fired more frequently in the high-frequency range. Under conditions of the ischiatic nerve blockade, a shift to an increase in the background firing frequency of the motor units related to intact gastrocnemius muscle seems to be related to increased motoneurone excitability occurring because of the contralateral denervation.

[Leukocyte and thrombocyte glycosaminoglycans in hemophilia A and von Willebrand's disease].

Aim: The study of glycosaminoglycanes (GAG) in leukocytes and platelets of patients with hereditary coagulopathy.

Materials And Methods: GAG concentration, composition and fraction identification were made in 25 patients with hemophilia A and 10 patients with Willebrand disease.

Results: In hemophiliacs, leukocytes contained low concentrations of GAG.

[The sonographic characteristics of hemophilic arthropathies].

The work presents findings of an ultrasonic examination of joints in 30 patients with hemophilia and in 15 healthy persons. Of 30 hemophilic patients 15 had hemarthroses and 15 had chronic hemorrhagic-destructive arthropathies. On the basis of the examinations carried out a conclusion was made about high informative value of sonography as a non-invasive diagnostic method and as estimation of the efficiency of treatment of hemophilic arthropathies.