Antimicrobial Efficiency of L. Derivates against Oral Biofilm-Associated Diseases-A Narrative Review.

L. (PlL) has been used for centuries in traditional medicine. The richness in antimicrobial biomolecules of Pll derivates can represent an alternative to chemically formulated agents used against oral infections.

Xerostomia: From Pharmacological Treatments to Traditional Medicine-An Overview on the Possible Clinical Management and Prevention Using Systemic Approaches.

Despite high incidence rates and severe complications, the management of xerostomia lacks clinical guidelines. The aim of this overview was to summarize the clinical experience derived from the last 10 years of treatments and prevention using systemic compounds. Results showed that the cytoprotective drug amifostine, and its antioxidant agents, are the most discussed as preventive agents of xerostomia in head and neck cancer (HNC) patients.

In Vitro Effect of Instrumentation Using Ultrasonication with and without Hydrogen Peroxide on the Removal of Biofilms and Spread of Viable Microorganisms in Aerosols.

Purpose: To evaluate the use of hydrogen peroxide as an adjunct to ultrasonication (US) in biofilm removal and whether it can limit the spread of viable microorganisms in the aerosol.

Materials And Methods: Multi-species biofilms were formed on dentin disks and titanium disks fixed on a plastic surface. After placing the specimens in a periodontal pocket model, an ultrasonic scaler was applied for 30 s, in part combined with 0.

In Vitro Activity of Propolis on Oral Microorganisms and Biofilms.

Natural products are being discussed as alternatives to commonly used chemicals in antimicrobial therapy. The study aimed to investigate the antimicrobial activity of propolis against microbial species associated with caries, periodontal disease, and Candida infections. Two commercially available ethanolic extracts of Brazilian and one of European propolis (EEP) were used.

Leaves and Fruits Preparations of L.: A Review on the Ethnopharmacological Uses and Implications in Inflammation and Infection.

There is an increasing interest in revisiting plants for drug discovery, proving scientifically their role as remedies. The aim of this review was to give an overview of the ethnopharmacological uses of L. (PlL) leaves and fruits, expanding the search for the scientific discovery of their chemistry, anti-inflammatory, antioxidative and antimicrobial activities.

The Pharmaceutical Ability of L. Leaves Essential Oil Against Periodontal Bacteria and sp. and Its Anti-Inflammatory Potential.

Background: Given the increasing request for natural pharmacological molecules, this study assessed the antimicrobial capacity of Pistacia lentiscus L. essential oil (PLL-EO) obtained from the leaves of wild plants growing in North Sardinia (Italy) toward a wide range of periodontal bacteria and including laboratory and clinical isolates sp., together with its anti-inflammatory activity and safety.

Effectiveness of Calcium Phosphate Desensitising Agents in Dental Hypersensitivity Over 24 Weeks of Clinical Evaluation.

Background: Calcium phosphate-based compounds are used to treat dental hypersensitivity (DH). Their long-term clinical behaviour needs further research. This study compared the 24-week effectiveness of Teethmate Desensitizer (TD), a pure tetracalcium phosphate (TTCP) and dicalcium phosphate dihydrate (DCPD) powder/water, to that of Dentin Desensitizer (DD), and Bite & White ExSense (BWE), both of calcium phosphate crystallites.

Antimicrobial Effect of and var. as Raw Extracts and Nanovesicles.

In view of the increasing interest in natural antimicrobial molecules, this study screened the ability of (TC) essential oil and var. (CLP) extract as raw extracts or incorporated in vesicular nanocarriers against and . After fingerprint, TC or CLP were mixed with lecithin and water to produce liposomes, or different ratios of water/glycerol or water/propylene glycol (PG) to produce glycerosomes and penetration enhancer vesicles (PEVs), respectively.

Thymus essential oil extraction, characterization and incorporation in phospholipid vesicles for the antioxidant/antibacterial treatment of oral cavity diseases.

The aim of the work was to extract, characterize, and formulate Thymus capitatus (Tymbra capitata) essential oil in phospholipid vesicles: liposomes, glycerosomes and Penetration Enhancer-containing Vesicles (PEVs). The steam-distilled essential oil was mainly composed of carvacrol. The oil was mixed with lecithin and water to produce liposomes, or different ratios of water/glycerol or water/propylene glycol (PG) to produce glycerosomes and PG-PEVs, respectively.

The role of adhesive materials and oral biofilm in the failure of adhesive resin restorations.

Purpose: To critically discuss adhesive materials and oral cariogenic biofilm in terms of their potential relevance to the failures of adhesive restorations in the oral environment.

Methods: The literature regarding adhesive restoration failures was reviewed with particular emphasis on the chemistry of adhesive resins, weakness in dentin bonding, water fluids, cariogenic oral biofilm and the relations that influence failures. Particular attention was paid to evidence derived from clinical studies.

A "Sacra Rappresentazione" of Saint Apollonia's Martyrdom.

The literary sources of Saint Apollonia's martyrdom and the evolution of Medieval and Renaissance religious drama are presented along with the compendium of a "Sacra Rappresentazione" from Italian Renaissance regarding Saint Apollonia's Martyrdom.

Phenolic Compounds in Extra Virgin Olive Oil Stimulate Human Osteoblastic Cell Proliferation.

In this study, we aimed to clarify the effects of phenolic compounds and extracts from different extra virgin olive oil (EVOO) varieties obtained from fruits of different ripening stages on osteoblast cells (MG-63) proliferation. Cell proliferation was increased by hydroxytyrosol, luteolin, apigenin, p-coumaric, caffeic, and ferulic acids by approximately 11-16%, as compared with controls that were treated with one vehicle alone, while (+)-pinoresinol, oleuropein, sinapic, vanillic acid and derivative (vanillin) did not affect cell proliferation. All phenolic extracts stimulated MG-63 cell growth, and they induced higher cell proliferation rates than individual compounds.

Osteogenesis from Dental Pulp Derived Stem Cells: A Novel Conditioned Medium Including Melatonin within a Mixture of Hyaluronic, Butyric, and Retinoic Acids.

Human dental pulp stem cells (hDPSCs) have shown relevant potential for cell therapy in the orthopedic and odontoiatric fields. The optimization of their osteogenic potential is currently a major challenge. Vascular endothelial growth factor A (VEGF A) has been recently reported to act as a major conductor of osteogenesis in vitro and in vivo.

Nanomaterials for Tissue Engineering In Dentistry.

The tissue engineering (TE) of dental oral tissue is facing significant changes in clinical treatments in dentistry. TE is based on a stem cell, signaling molecule, and scaffold triad that must be known and calibrated with attention to specific sectors in dentistry. This review article shows a summary of micro- and nanomorphological characteristics of dental tissues, of stem cells available in the oral region, of signaling molecules usable in TE, and of scaffolds available to guide partial or total reconstruction of hard, soft, periodontal, and bone tissues.

Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage.

Background: The irradiation of head and neck cancer (HNC) often causes damage to the salivary glands. The resulting salivary gland hypofunction and xerostomia seriously reduce the patient's quality of life.

Purpose: To analyze the literature of actual management strategies for radiation-induced hypofunction and xerostomia in HNC patients.

The use of probiotic strains in caries prevention: a systematic review.

This paper aims to provide a systematic review of the caries-prevention effect of probiotics in human. The hypothesis was that the administration of probiotic strains might play a role in caries lesion prevention and in the control of caries-related risk factors. The main relevant databases (Medline, Embase) were searched.

TEM morphological characterization of a one-step self-etching system applied clinically to human caries-affected dentin and deep sound dentin.

Purpose: To examine morphologically the hybrid layer of one-step self-etching adhesive, Clearfil S3 Bond (S3bond), in caries-affected dentin (CAD) and deep sound dentin (DSD) cavities performed clinically. For a comparative group, the two-step self etching adhesive Clearfil Protect Bond (Pbond) was used in a similar clinical situation.

Methods: This study was carried out on carious and sound teeth clinically selected for extraction.

Short-term response of three resin-based materials as desensitizing agents under oral environmental exposure.

Objective: This paper focuses on clinical responses after 7 days of oral exposure to two resin-based materials as desensitizing agents compared to a fluoride varnish and on morphological and analytical study as a means to elucidate the mechanism of action.

Materials And Methods: The elemental composition of Vertise™ Flow (VF), Universal Dentine Sealant (UDS) and Flor-Opal® Varnish (FOV) were investigated by using an X-ray energy dispersive spectrometer (EDX) in conjunction with a scanning electron microscope (SEM). SEM morphology of the material-treated dentine surfaces and pain reduction ability according to the Visual Analogue Scale (VAS) were evaluated in selected hypersensitive teeth.

A systematic review on fluoridated food in caries prevention.

Objective: This paper aims to provide a systematic review of the caries-prevention effect of fluoridated food, excluding water. The main aim of this review was to evaluate the presence of scientific evidence relating to the effects of fluoride intake via food on the occurrence of carious lesions. The outcome was defined as a clinical outcome, so only papers evaluating a decrease in caries indices were included.

Current dental adhesives systems. A narrative review.

Adhesive dentistry is based on the development of materials which establish an effective bond with the tooth tissues. In this context, adhesive systems have attracted considerable research interest in recent years. Successful adhesive bonding depends on the chemistry of the adhesive, on appropriate clinical handling of the material as well as on the knowledge of the morphological changes caused on dental tissue by different bonding procedures.

Influence of cavity configuration on microleakage around Class V restorations bonded with seven self-etching adhesives.

Purpose: The purpose of this study was to evaluate microleakage around Class V resin composite restorations with different cavity configurations, bonded with one of seven self-etching materials or with an adhesive using the total-etch technique.

Materials And Methods: Ninety-six human molars and premolars were randomly assigned to eight groups and bonded with one of seven self-etching adhesives--Prompt-L-Pop (3M ESPE, St. Paul, MN, USA), Adper Prompt-L-Pop (3M ESPE), Clearfil SE Bond (Kuraray Medical, Okayama, Japan), Prime & Bond NT/NRC (Dentsply DeTrey, Konstanz, Germany), Xeno III (Dentsply DeTrey), One-Up Bond (Tokuyama Dental, Tokuyama, Japan), AdheSE (Ivoclar Vivadent, Schaan, Liechtenstein)-or with Prime & Bond NT (Dentsply DeTrey) using a separate total-etch technique.

Influence of marginal bevels on microleakage around Class V cavities bonded with seven self-etching agents.

Purpose: To evaluate microleakage around Class V resin-based composite restorations in box-shaped cavities with and without marginal bevels, bonded with one of seven self-etching materials and a non-self etching system.

Methods: 120 extracted human premolars were randomly assigned to eight groups for bonding with the following self-etching agents: Prompt-L Pop, Adper Prompt, Clearfil SE, Prime& Bond NT with NRC, Xeno111, One-Up Bond, AdheSe, or Prime & Bond NT using a total etch technique (36% H2PO4). Box cavities were cut in both the lingual and buocal surfaces.

Microleakage around a low-shrinkage composite cured with a high-performance light.

Purpose: To compare microleakage of Class V restorations filled with a novel low-shrinkage resin-based composite cured by a high intensity light and a combination of controls including a conventional composite cured by conventional and soft-start regimes.

Methods: Forty-two intact premolar and molar teeth were randomly assigned to seven groups and filled with a low-shrinkage composite or a conventional composite, bonded with one of two bonding materials (Excite or Prime&Bond NT) and cured with either a high intensity light, a soft-start regime or a conventional light regime. Cavities were cut in both the buccal and lingual aspects of each tooth with half of the preparation in enamel and half in dentin/cementum.