DNA-Damaging Effect of Different Wavelength (206 and 257 nm) Femtosecond Laser Pulses.

The purpose of this study was to investigate the possible cytotoxic and genotoxic impact of new-generation 206 nm femtosecond solid-state laser irradiation on murine skin cells in vitro, and to compare the cell and DNA damage caused by different wavelength (206 vs. 257 nm) femtosecond laser pulses. The first attempts to evaluate the possible genotoxic impact of ultrashort laser pulses on the murine bone marrow cells in vitro revealed the unlooked-for DNA-damaging effect.