Publications by authors named "Eghosa Eguakun"
Article Synopsis
- Stress plays a significant role in triggering neuropsychiatric disorders and relapse in addiction, suggesting that targeting the stress response may help treat substance use disorders with medications like anxiolytics.
- The research highlights that α-adrenergic receptors (α-ARs) in the brain, particularly in the extended amygdala, are important for modulating stress responses, and these receptors function similarly even in non-noradrenergic areas.
- The study found that guanfacine, an α2A-AR agonist, enhances neuronal activity in the dorsal bed nucleus of the stria terminalis (dBNST) and has the potential to manage craving and anxiety, although its impact on relapse remains unclear due to competing brain actions.
